Mr Nicola de´ Liguori-Carino

 Professional experience

• More than 20 years of experience
• Consultant HPB, Laparoscopic and General Surgeon, North Manchester General Hospital NHS Trust (2009 - 2014)
• Consultant Hepatobliary and Pancreatic Surgeon, Manchester Royal Infirmary, Manchester University Hospitals FT 2014-present

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 Sub-specialties

• Liver cancers
• Pancreatic cancer
• Gallstones
• Inguinal hernias
• Hernias
• Key hole / laparoscopic surgery
• Irreversible electroporation (IRE)
• Disease of the biliary system
• Incisional Hernias
• Laparoscopic cholecystectomy
• Laparoscopic and open hepatobiliary
• Pancreatic and digestive surgery

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 Teaching posts

• Clinical Supervisor for FY, CT and ST Training doctors 2010-present

 Education

• Thesis , Universita degli Studi di Roma "Tor Vergata" (2002)
• MD Thesis, Perioperative use of the LiMON method of indocyanine green elimination measurement to detect post-hepatectomy liver failure. University of Liverpool and University of Rome Tor Vergata (2008)

 Publications and conferences

• 31) Tufo A, Dunne D, Manu N, Lacasia C, Jones L, de Liguori Carino N, Malik AK, Poston GJ, Fenwick S. Changing outlook for colorectal liver metastasis resection in the elderly. Eur J Surg Oncol. In press 2018
• 30) de Liguori Carino N, O’Reilly DA, Siriwardena AK, Valle JW, Radhakrishna G, Pihlak R, McNamara MG. Irreversible electroporation in pancreatic ductal adenocarcinoma: is there a role in conjunction with conventional treatment? Eur J Surg Oncol. 2018, 1-8. DOI information: 10.1016/j.ejso.2018.07.04
• 29) Montroni I, Ugolini G, Saur NM, Spinelli A, Rostof S, Millan M, Wolthuis A, Daniels IR, Hompes R, Penna M, Furst A, Papamichael D, Desai AM, Cascinu S, Gerard JP, Myint AS, Lemmens VEPP, Berho M, Lawler M, de Liguori Carino N, Potenti F, Nanni O, Altini M, Beets G, Rutten H, Winchester D, Wexner SD, Audisio RA. Personalized management of elderly patients with rectal cancer: expert recommendations of the European Society of Surgical Oncology, European Society of Coloproctology, International Society of Geriatric Oncology, American College of Surgeons Commission on Cancer Eur J Surg Oncol. 2018, 1-18, DOI: 10.1016/j.ejso.2018.08.003
• 28) Malik AK, Filobbos R, Manoharan A, Harvey N, O'Reilly DA, de Liguori Carino N. A case report of an angiomyxoma in the liver. Ann R Coll Surg Engl. 2018 Apr;100(4):e81-e84. doi: 10.1308/rcsann.2018.0042. Epub 2018 Mar 15.
• 27) Salih Z, Lamarca A, Nonaka D, Hubner RA, de Liguori-Carino N, McNamara MG, Fulford P, Minicozzi A, O'Dwyer S, Chakrabarty B, Valle JW. The dark side of T1 non-appendiceal small bowel neuroendocrine tumors. Hum Pathol. 2017 May 9. pii: S0046-8177(17)30146-6.
• 26) Khaled YS, Fatania K, Barrie J, De Liguori N, Deshpande R, O'Reilly DA, Ammori BJ. Matched Case-Control Comparative Study of Laparoscopic Versus Open Pancreaticoduodenectomy for Malignant Lesions. Surg Laparosc Endosc Percutan Tech. 2017 Feb 16.
• 25) Alessandri G, Amodio A, Landoni L, De' Liguori Carino N, Bassi C. Recurrent acute pancreatitis in bowel malrotation. Eur Rev Med Pharmacol Sci. 2016 Nov;20(22):4719-4724.
• 24) Huisman MG, Veronese G, Audisio RA, Ugolini G, Montroni I, de Bock GH, de Liguori Carino N, van Leeuwen BL; PREOP study group. Poor nutritional status is associated with other geriatric domain impairments and adverse postoperative outcomes in onco-geriatric surgical patients - A multicentre cohort study. Eur J Surg Oncol. 2016 Jul;42(7):1009-17
• 23) Parkin E, O'Reilly DA, Plumb AA, Manoharan P, Rao M, Coe P, Frystyk J, Ammori B, de Liguori Carino N, Deshpande R, Sherlock DJ, Renehan AG. Digital Histology Quantification of Intra-hepatic Fat in Patients undergoing Liver Resection. Eur J Surg Oncol. 2015 Aug;41(8):1020-7.
• 22) Khaled YS1, Malde DJ, Packer J, De Liguori Carino N, Deshpande R, O'Reilly DA, Sherlock DJ, Ammori BJ. A Case-matched Comparative Study of Laparoscopic Versus Open Distal Pancreatectomy. Surg Laparosc Endosc Percutan Tech. 2015 Aug; 25(4):363-7
• 21) Huisman MG, Audisio RA, Ugolini G, Montroni I, Stabilini C, Vigano A, Spiliotis J, de Liguori Carino N, Farinella E, Stanojevic G, Milica N, Th Veering B, Reed MW, Ponnandai, SS, de Bock GH, van Leeuwen BL. Screening for predictors of adverse outcome in onco-geriatric surgical patients. A multicenter prospective cohort study. Eur J Surg Oncol. 2015 Apr 13. pii: S0748-7983(15)00375-3.
• 20) Khaled YS, Malde DJ, Packer J, Fox T, Laftsidis P, Ajala-Agbo T, De Liguori Carino N, Deshpande R, O'Reilly DA, Sherlock DJ, Ammori BJ. Laparoscopic versus open cystgastrostomy for pancreatic pseudocysts: a case-matched comparative study. J Hepatobiliary Pancreat Sci. 2014 Jul 31. doi: 10.1002/jhbp.138
• 19) Bonanni L, de Liguori Carino N, Deshpande R, Ammori BJ, Sherlock DJ, Valle JW, Tam E, O’Reilly DA. A comparison of diagnostic imaging modalities for colorectal liver metastases. Eur J Surg Oncol. 2014 May;40(5):545-50.
• 18) Huisman MG, van Leeuwen BL, Ugolini G, Montroni I, Spiliotis J, Stabilini C, de Liguori Carino N, Farinella E, de Bock GH, Audisio RA. "Timed Up & Go": a screening tool for predicting 30-day morbidity in onco-geriatric surgical patients? A multicenter cohort study. PLoS One. 2014 Jan 24;9(1):e86863.
• 17) O’Reilly DA, Edmiston R, Bijoor P, de Liguori Carino N, Deshpande R, Ammori BJ, Sherlock DJ. Early experience with a Hepatobiliary and Pancreatic Quality Improvement Program. BMJ Qual Improv Report 2013;2: doi:10.1136/bmjquality.u201158.w721
• 16) Khoja L, Mitchinson C, Brown D, Zhou C, Morris K, O'Reilly D, Deshpande R, de Liguori Carino N, Clack G, Hughes AM, Valle JW, Dive C. Pancreatic circulating tumor cells: Where are they? Journal of Clinical Oncology 30, no. 15_suppl 2012.30.
• 15) Dajani K, O’Reilly DA, de Liguori Carino N, Ghaneh P, Poston G, Wu A. The Prognostic Significance of the Preoperative Full Blood Count After Resection Of Colorectal Liver Metastases. HPB Surgery. 2009:425065. Epub 2009 Sep 8.
• 14) de Liguori Carino N, Manzia TM, Tariciotti L, Berlanda E, Orlando G, Tisone G. Liver Transplantation for Primary Hepatic Carcinoid Tumor. Report of a Case and Review of the Literature. Transplant Proc. 2009 May; 41(4):1386-9.
• 13) de Liguori Carino N, O’Reilly DA, Dajani K, Ghaneh P, Poston G, Wu A. Perioperative use of the LiMON method of indocyanine green elimination measurement for the prediction and early detection of post-hepatectomy liver failure. Eur J Surg Oncol. 2009 Feb 27.
• 12) Morris-Stiff G, Gomez D, de Liguori Carino N, Prasad KR. Surgical management of hepatocellular carcinoma: is the jury still out? Surgical Oncology. 2008 Dec 3.
• 11) Gravante G, de Liguori Carino N, Manzia TM, Orlando G. Primary carcinoids of the liver. A review of symptoms, diagnosis and treatments. Digestive Surgery. 2008;25(5):364-8.
• 10) de Liguori Carino N , van Leeuwen BL, Ghaneh P, Wu A, Audisio RA, Poston GJ. Liver resection for colorectal liver metastases in older patients. Critical Review In Oncology and Hematology. 2008 Sep;67(3):273-8.
• 9) Stoeder D, de Liguori Carino N, Marshall E, Poston GJ, Wu A. Extensive necrosis of visceral melanoma metastases after immunotherapy. World J Surg Oncol. 2008 Mar 4;6:30
• 8) Orlando G, Gravante G, D'Angelo M, de Liguori Carino N, Di Cocco P, Scelzo C, Famulari A, Pisani F. A renal graft with six arteries and double pelvis. Transpl Int. 2008 Jun;21(6):609-11.
• 7) Orlando G, Sabbà C, de Liguori Carino N, Scalzo C, Tariciotti L, Bonanni L, D’ Anglo M, Baiocchi L, Lerut J, Tisone G. Non-transplant surgical approach to liver-based hereditary haemorrhagic telangiectasia: a first case report. Liver Int. 2008 Apr;28(4):574-7.
• 6) Orlando G, Baiocchi L, Cardillo A, Iaria G, de Liguori Carino N, De Luca L, Ielpo B, Tariciotti L, Angelico M, Tisone G. Switch to 1.5 grams MMF monotherapy for CNI-related toxicity in liver transplantation is safe and improves renal function, dyslipidemia, and hypertension. Liver Transpl. 2007 Jan;13(1):46-54.
• 5) Manzia TM, de Liguori Carino N, Orlando G, Toti L, De Luca L, D’Andria D, Cardillo A, Anselmo A, Cascinai CU, Tisone G. Use of mycophenolate mofetil in liver transplantation: a literature review. Transplant Proc. 2005 Jul-Aug;37(6):2616-7.
• 4) Muzi F, Orlando G, Ielpo B, Anselmo A, Sabato Ceraldi S, de Liguori Carino N, Manzia T, D'Andria D, Tariciotti L, Angelico M, Tisone G Amantadine monotherapy is ineffective in the treatment of hepatitis C virus recurrence in the post-liver transplantation setting. Transplant Proc. 2005 May;37(4):1705-7.
• 3) Tisone G, Manzia TM, Zazza S, de Liguori Carino N, Ciceroni C, De Luca I, Toti L, Casciani CU. Marginal donors in liver transplantation. Transplant Proc .2004 Apr;36(3):525-6.
• 2) Buonomo O, Felici A, Granai AV, Piccirillo R, de Liguori Carino N, Guadagni F, Mariotti S, Orlandi A, Tipaldi G, Cipriani C, Chimenti S, Cervelli V, Casciani CU, Roselli M. Sentinel lymphadenectomy in cutaneous melanoma. Tumori. 2002 May-Jun;88(3):S49-51.
• 1) Buonomo O, Granai AV, Felici A, Piccirillo R, de Liguori Carino N, Guadagni F, Polzoni M, Mariotti S, Cipriani C, Simonetti G, Cossu E, Schiaroli S, Altomare V, Cabassi A, Pernazza E, Casciani CU, Roselli M. Day-surgical management of ductal carcinoma in situ (DCIS) of the breast using wide local excision with sentinel node biopsy. Tumori. 2002 May-Jun;88(3):S48-9.
• 32) Siriwardena AK, Jegatheeswaran S, Mason JM, Baltatzis M, Chan A, Sheen AJ, O'Reilly D, Jamdar S, Deshpande R, de Liguori Carino N, Satyadas T, Qamruddin A, Hayden K, Parker MJ, Butler J, Rajai A, McIntyre B PROCalcitonin-based algorithm for antibiotic use in Acute Pancreatitis (PROCAP): study protocol for a randomised controlled trial. Trials. 2019 Jul 29;20(1):463. doi: 10.1186/s13063-019-3549-3.

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 Professional membership

• General Medical Council (GMC)
• British Medical Association (BMA)
• European-African Hepato-Pancreato-Biliary Association (EAHPBA)
• International Hepato-Pancreato Biliary Association (IHPBA)
• Association of Upper GI Surgeons of Great Britan and Ireland (AUGIS)
• European Society of Surgical Oncology (ESSO)

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