Prostate cancer treatment: how to reduce the side effects of radiotherapy

Autore: Mr Neil Haldar
Pubblicato:
Editor: Laura Burgess

If you are going to have radiotherapy as part of your prostate cancer treatment, you may be researching the possible side effects of the procedure. Most patients will experience an increase in the need to urinate, a weak urinary stream, difficulty even starting urination and diarrhoea in the weeks after radiotherapy.

Thankfully, there is a follow-up procedure known as SpaceOAR® Hydrogel, which can be used to minimise the harmful and unpleasant side effects of prostate radiotherapy. Consultant urologist Mr Neil Haldar explains how it works, the benefits and its effectiveness.

What is the SpaceOAR® Hydrogel?

The SpaceOAR® Hydrogel was designed to reduce radiation exposure to the organs surrounding the prostate during prostate radiotherapy. The reduction in radiation exposure to surrounding organs can reduce the side effects such as rectal bleedingloose bowel motions, urinary incontinence and impotence. (See references at the end of this article).
 

What happens during the procedure?

SpaceOAR® Hydrogel is a soft gel implanted between the prostate and rectum to create a space. This space is important as it pushes the rectum away from the prostate and therefore, the radiotherapy field.

This allows a maximum dose of radiotherapy to be delivered to the prostate gland and therefore to the prostate cancer whilst avoiding unnecessary irradiation of surrounding tissue. This, therefore, minimises harmful and potentially unpleasant side effects.

The gel is implanted through a minimally invasive procedure under ultrasound guidance. The SpaceOAR procedure is usually performed under local anaesthetic. The gel remains in place for up to six months, whilst it is naturally absorbed by the patient’s body.
 

WATCH A VIDEO ON THE PROCEDURE

How safe is SpaceOAR® hydrogel?

SpaceOAR® hydrogel has been implanted in over 50,000 men worldwide and evaluated in over 60 publications. The studies have consistently found that SpaceOAR is safe and effective.
 

What are the benefits?

The studies in patients undergoing prostate cancer radiotherapy report benefits, including:
 

  • A reduction in rectal toxicity from radiation from 9.2% in the control group vs 2% in the group receiving the SpaceOAR gel.
  • A reduction in urinary incontinence from 19.6% in the control group to 4.3% in the SpaceOAR hydrogel group.
  • A reduction in the decline of bowel Quality of Life from 20.5% in the control group vs 5.4% in the hydrogel spacer group.
  • Potent men were twice as likely to retain erections sufficient for intercourse in the group who received the hydrogel rectal spacer before prostate radiotherapy. Approximately 37.5% control vs 66.7% treated. (See references).



Mr Haldar is an expert in treating prostate cancer, benign prostate enlargement, prostate removal and kidney stones. Do not hesitate to book an appointment for a consultation now via his Top Doctor’s profile.
 

 

References: 
1) Hamstra D, Mariados N, Sylvester J et al. Continued Benefit to Rectal Separation for Int J Radiat Oncol Biol Phys. 2017 Apr 1;97(5):976-985. DOI: 10.1016/j.ijrobp.2016.12.024. Epub 2016 Dec 23.

2) Hamstra D, et al. Evaluation of sexual function on a randomised trial of a prostate rectal

3) Hamstra DA, Mariados N, Sylvester J et al. Sexual quality of life following prostate intensity-modulated radiation therapy (IMRT) with a rectal/prostate spacer: Secondary analysis of a phase 3 trial. Pract Radiat Oncol. 2018 Jan - Feb;8(1):e7-e15. DOI: 10.1016/j.prro.2017.07.008. Epub 2017 Jul 19.

4) SpaceOAR, What is SpaceOAR® Hydrogel?: https://www.businesswire.com/news/home/20170829005780/en [accessed February 2018]

*Tradotto con Google Translator. Preghiamo ci scusi per ogni imperfezione

Mr Neil Haldar
Urologia

Il signor Neil Haldar è un chirurgo urologico consulente leader con sede nel Buckinghamshire . Dopo essersi diplomato alla King's College Medical School nel 1992, il sig. Haldar è entrato a far parte del programma di formazione Oxford Junior Surgical. Da lì il signor Haldar è stato insignito dal Royal College of Surgeons della Fellowship di ricerca della Fondazione Allinson in cui è stato in grado di intraprendere il suo master presso il Dipartimento di Chirurgia di Nuffield a Oxford. Una volta completato il suo corso di specializzazione urologica, il sig. Haldar è diventato il responsabile clinico dell'urologia laparoscopica presso il Buckinghamshire NHS Trust.

Mr Haldar è ben pubblicato nella maggior parte degli aspetti di urologia, con un focus attuale sulla ricerca di Enhanced Recovery Surgery. Le principali specialità cliniche di Mr Haldar includono il cancro della vescica, della prostata e del rene. È anche un esperto in chirurgia ad accesso minimo e nel 2008 è stato uno dei primi chirurghi britannici a eseguire una nefrectomia laparoscopica transperitoneale e extraperitoneale.

*Tradotto con Google Translator. Preghiamo ci scusi per ogni imperfezione

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