Colon capsule endoscopy: making the uncomfortable more comfortable

Written by: Dr Amit Chattree
Edited by: Sarah Sherlock

For decades, a colonoscopy has been the gold standard method to have an examination of the large bowel. However, a new technique called a colon capsule endoscopy is revolutionising colonic assessment by being both non-invasive and painless. Leading consultant gastroenterologist Dr Amit Chattree provides further detail about what it is and what a patient can expect from the procedure in this article.


colon capsule endoscopy


What is a colon capsule endoscopy?

Colon capsule endoscopy is an examination of the large bowel of the colon using a small video capsule pill with a camera that is swallowed. It is entirely painless and travels through your colon taking images and a video, and it can be used to examine the entire line of your colon looking for pathology in a similar way to a colonoscopy. Like colonoscopy, colon capsule endoscopy can be used to detect various pathologies such as polyps, tumours, cancers, diverticular disease, haemorrhoids, and bleeding blood vessels (angiodysplasia).



How does it differ from a colonoscopy? Is it as good as a colonoscopy?

It is entirely non-invasive and painless unlike the colonoscopy, which is an invasive procedure where you have an endoscopic camera inserted 80 to 90 centimetres internally. In the appropriate setting, the diagnostic yield is comparable to colonoscopy with a very high diagnostic yield. The test can also be modified to examine both the small and large bowel in one test which is another major benefit. Like colonoscopy, bowel preparation drinks are required to cleanse the bowel to allow adequate views. Additional special booster drinks that help the capsule go through your intestines and take the video are also needed.



Who might benefit from a colon capsule endoscopy?

Colon capsule endoscopy is an excellent option for patients who cannot have a colonoscopy because:


  • They have undergone previous operations that make their bowel impassable.
  • They have had a very bad experience with a colonoscopy (e.g. very painful procedure).
  • A previous complication from a colonoscopy.
  • Significant anxiety about undergoing an invasive procedure such as colonoscopy.



What conditions can be diagnosed using a colon capsule endoscopy?

There most common conditions diagnosed with a colon capsule endoscopy are:


  • colitis
  • angiodysplasias (abnormality in blood vessels)
  • polyps
  • diverticulitis
  • cancer



How long does it take to pass?

With the boosters, it should pass out after about eight or nine hours. You don’t need to retrieve it as it just gets passed out in the toilet.



Is the test safe? Can the capsule get stuck? When should a medical professional be seen?

Colon capsule endoscopy is a very safe test. In addition, prior to undergoing the procedure you will undergo a detailed pre-assessment consultation to ensure that any special considerations are accounted for. This includes the risk of the capsule getting stuck in the intestines. This risk is generally extremely low (less than 0.5 per cent). In patients in whom there might be additional concerns, a patency capsule (a dummy pill of the same size that dissolves after 30 hours) can be used prior to colon capsule endoscopy to ensure then we know it’s entirely safe to proceed. With a successful patency capsule, the risk of a retained capsule is reduced further still.


Follow-up checks after the procedure will also take place. If the capsule has not been seen to pass out after two weeks, please contact your medical professional but do not be alarmed as usually the capsule will have passed out in stool unseen.



If you need to have a colonoscopy but are more interested in having a colon capsule endoscopy, you can go to Dr Chattree's profile and book a consultation.

By Dr Amit Chattree

Dr Amit Chattree is an exceptionally skilled and renowned Consultant Gastroenterologist with subspecialty in expertise in luminal gastroenterology including inflammatory bowel disease and endoscopy. He worked in world-leading centres during his training in North and Central London, gaining valuable expertise in treating the most complex gastrointestinal conditions.  He runs an expert practice and receives referrals from colleagues at many centres regionally, including for second opinions, and manages a diverse range of conditions  and symptoms including inflammatory bowel disease, bowel cancer, general liver disease, coeliac disease, dyspepsiagastrointestinal cancer (upper and lower GI cancers), small bowel conditions, diarrhoea, rectal bleeding, gastrointestinal polyps, bowel cancer screening and complex abdominal pain.

Dr Chattree is an expert in diagnostic and therapeutic endoscopic procedures with outstanding outcomes. During his training, he underwent an advanced endoscopy fellowship at the University Hospital of North Tees.  He is an accredited colonoscopist for the NHS bowel cancer screening programme and leads the tertiary small bowel service at South Tyneside and Sunderland NHS Foundation Trust, the tertiary regional referral centre for small bowel disease for the North East and Cumbria. Dr Chattree performs a wide range of diagnostic and therapeutic endoscopic procedures: from small bowel endoscopy procedures (capsule endoscopy, single balloon enteroscopy, double-balloon enteroscopy) to upper and lower GI endoscopies including bowel cancer screening, complex polypectomy, transnasal endoscopy, luminal stenting, dilatation and therapeutic endoscopy.

Dr Chattree has obtained numerous major achievements during his career. He is the lead author of the British Society of Gastroenterology Guidelines for the management of large colorectal polyps and also developed the world’s first framework for the management of large polyps.  In addition he has published multiple articles in peer reviewed journals and was awarded a prize by the British Society of Gastroenterology for his work in 2015.  He has been an invited speaker and presented his own research at national and international conferences. He greatly contributes to research in small bowel disease, inflammatory bowel disease research and endoscopy and has been a principal investigator for numerous trials.  He is highly regarded by both patients and colleagues and regularly receives outstanding feedback for his work. 

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