Understanding prostate health

Written by: Mr Rick Popert
Published: | Updated: 08/04/2020
Edited by: Bronwen Griffiths

If you are suspected of having problems with your prostate, normally, the first diagnostic step would be a PSA test. Following the results of this, a biopsy may be performed as well. If you are diagnosed with an enlarged prostate, there are several treatment methods available, including HoLEP. Mr Rick Popert, a leading urologist, explains how a prostate biopsy is performed, what HoLEP is and shares advice on when men should start checking their prostate.

When should men start checking their prostate and how frequently?

Prostate cancer diagnosis really starts from the age of 40 in my view. If a man has a family history of prostate cancer, they should have their PSA levels (prostate specific antigen) checked starting at the age of 40. It should probably be repeated every two or three years until the age of 50 when it should be done annually.

The critical thing with the PSA blood test is to know what your baseline is. If one finds that the PSA is slowly increasing over time, that may simply reflect benign enlargement of the prostate, but there is also the possibility that prostate cancer may be developing silently within the prostate, which may require treatment.

Most routine medicals done as part of a health assessment will include the PSA blood test from the age of 50. Do not be afraid to ask for the PSA blood test from your GP though. If you wish to have the PSA checked, they should do it for you. They may explain that the PSA blood test is prostate-specific, not prostate cancer specific. But take it from me, it is better to know what your PSA level is at the age of 40 or 50 and follow it yourself and if it goes up, seek specialist attention.

How is a prostate biopsy carried out?

In order to biopsy the prostate, you have to visualise it with an ultrasound probe, which is about the size of the width of a thumb. It is placed into the back passage so that we can see the prostate gland in situ.

The options for doing the biopsy are either:

  • With a biopsy gun that is fired through the wall of the rectum directly into the prostate. This is called a trans-rectal prostate biopsy.
  • Alternatively, and in my view, much more safely and effectively, we can actually go through the skin between the back passage and the scrotum. That area of skin is called the perineum. In this situation, we do a transperineal biopsy. This avoids going through the back passage which is dirty. It also allows us to take biopsies all the way around the outside of the prostate so it is actually a much better method.
  • We also have a method called an MRI-ultrasound fusion targeted biopsy, which in my view is the most accurate way of diagnosing a potentially high-risk prostate cancer. We use the information that you can get from an MRI scan. If we can see an area of abnormality on the MRI scan, we can do targeted biopsies of that area. In some patients, we can take the MRI images and fuse those on a computer software program with the ultrasound images so that we can take a very accurate biopsy.

What is a holmium laser prostatectomy (HoLEP)?

The prostate gland gets bigger as you get older. In some men, the prostate gland can get very big indeed. Most prostate cancers exist in the outer peripheral portion of the prostate gland. The central bit is the bit that gets bigger as you get older and it gets bigger in men (and dogs!), restricting the flow of urine. If you try to remove that central core of the prostate gland through an open operation, it can cause very significant bleeding.

The holmium laser prostate enucleation allows us to do that same operation, but through the penis without needing to make an incision. Most patients will regain their urinary control very quickly after the operation. For people with a very large prostate, it is the safest way of managing benign enlargement to the prostate. This is not prostate cancer. This is surgery for patients who just got a very big, enlarged prostate.

My experience in holmium laser prostate surgery is more than 15 years. I have done over a thousand of these operations. I have to say, it is the most effective way of improving a man’s urinary flow if they have significant prostate enlargement. However, it is critical that the surgeon that you go to understands the anatomy of the prostate and how to carry out this form of surgery safely.

By Mr Rick Popert
Urology

Mr Rick Popert was appointed as a consultant to Guy’s & St Thomas’ Hospitals in 1996, having completed his higher surgical training at Guy's and urological research at King's College Hospital.  Mr Popert's clinical expertise is in the comprehensive evaluation and surgery of benign and malignant prostatic disease.
 
PROSTATE CANCER SURGERY:
- Robotic Prostatectomy with the Da Vinci Robot  – Conventional, Retzius Sparing & Salvage Prostatectomy

He successfully transferred his experience from conventional open radical prostatectomy (over 200 cases between 1997 and 2005) to the Da Vinci robotic assisted approach in 2006 and since then has carried out over 800 robotic prostatectomies. He has the UK’s largest experience of salvage prostatectomy following radiotherapy and brachytherapy and has helped to establish a tertiary referral “salvage surgery” clinic at Guy’s Hospital. He is also establishing a “Retzius sparing” surgery programme at Guy’s, in selected cases.
 
PROSTATE BRACHYTHERAPY: 
- Focussed Dynamic Prostate Brachytherapy – Day Case Procedure for low to intermediate risk prostate cancer
- Brachytherapy as a boost to External Beam Radiotherapy for intermediate to high risk prostate cancer.
 
He has the UK's largest experience of single visit dynamic intra-operative “focussed” prostate brachytherapy and has carried out over 900 of these cases since 2004. The oncology team with Dr Stephen Morris and Dr Ronald Beaney, Consultant Clinical Oncologists. can also offer brachytherapy as a “boost” to external beam radiotherapy and the insertion of Fiducial Markers and the SpaceOAR rectal spacer to reduce rectal dosing.
 
PRECISION PROSTATE CANCER DIAGNOSTICS:
- MRI – US Fusion Targeted Prostate Biopsies + Systematic Transperineal Biopsies (General Anaesthetic)
- Precision Point – 2 Puncture Targeted and Systematic Transperineal Biopsy (Local Anaesthetic)
 
He is an expert in Precision Prostate Diagnostics and has developed a rapid access prostate MRI assessment service with Dr Giles Rottenberg, Consultant Radiologist, combined with a unique systematic transperineal biopsy approach providing accurate tumour localisation, an approach that has been further enhanced by the technique of MRI US Fusion Targeted biopsy of the prostate which he introduced in March 2012. Over the last year he has been evaluating the Precision Point Transperineal Access System, which facilitates targeted and systematic transperineal biopsies using a 2 puncture approach under local anaesthetic.
 
BENIGN PROSTATIC DISEASE:
- Holmium Laser Prostate Enucleation for benign prostate disease - HoLEP
- Prostate Arterial Embolisation - PAE
 
For benign prostatic disease, he has one of the UK's longest experience of holmium laser prostatectomy (HoLEP), establishing a service at Guy’s in 2002. He has carried out over 800 holmium laser enucleations with reduced bleeding and length of stay in patients with prostate volumes larger than 100 cc compared with standard transurethral prostatectomy (TURP), the only hospital in London to do so. He established a Prostatology service at Guy’s Hospital attracting tertiary referrals from across London of very large prostates. In 2014 he introduced a prostate arterial embolisation service in association Dr Tarun Sabharwal, Consultant Interventional Radiologist.  This is an alternative to the surgical management of benign prostatic disease avoiding the complications of urinary incontinence, erectile and ejaculatory dysfunction. 

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