What is being analysed?

This analysis measures the levels of vitamin B12 and folate (also known as vitamin B9) in the blood.

What does the result mean?

The result indicates the concentration of these essential vitamins in the bloodstream, which is crucial for various bodily functions, including DNA synthesis, red blood cell formation, and nerve function.

Why do the analysis?

The analysis of vitamin B12 and folate levels is essential for diagnosing deficiencies, which can lead to anaemia, neurological issues, and other health complications. Identifying deficiencies early allows for prompt intervention and treatment.

When to do the analysis?

This analysis is typically recommended when symptoms of Vitamin B12 or folate deficiency are present, such as fatigue, weakness, numbness or tingling in the extremities, difficulty concentrating, or unexplained anaemia. Additionally, it may be ordered as part of routine health screenings, especially for individuals with risk factors such as gastrointestinal disorders or malabsorption syndromes.

What sample is required?

A blood sample is required for this analysis, usually obtained through a simple venipuncture procedure.

Is any type of prior preparation necessary?

No specific prior preparation is typically required for this analysis. However, it is advisable to inform your doctor about any medications or supplements you are taking, as they may affect the results.

How is it used?

The analysis of Vitamin B12 and folate levels helps healthcare providers diagnose deficiencies and monitor treatment effectiveness in individuals receiving supplementation or undergoing therapy for related conditions.

What are the normal values?

Normal values for vitamin B12 typically range from 200 to 900 picograms per millilitre (pg/mL), while normal values for folate range from 2.5 to 20 nanograms per millilitre (ng/mL).

What does it mean to have altered values?

Elevated levels of vitamin B12 are usually not a cause for concern, as the body typically excretes excess amounts. However, low levels of vitamin B12 or folate can indicate deficiencies, which may require supplementation or dietary changes. Deficiencies can lead to symptoms such as anaemia, neuropathy, cognitive impairment, and increased risk of cardiovascular disease.

Table: Normal values for vitamin B12 and folate