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Dr Melita IrvingClinical Genetics in Central London
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Dr Melita Irving

Clinical Genetics in Central London

MBBS MD(Res) FRCPCH BSc(Hons)
GMC: 4311733

5.047reviewsReview

Expert in:
Developmental delay
Genetic disorders
Achondroplasia
Skeletal dysplasia
Genetic testing
  • Information
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Professional statement

Dr Melita Irving is an expert London-based consultant and honorary reader in clinical genetics.  After initially training in paediatrics, she now specialises in genetic conditions, and has extensive experience in diagnosing and managing a wide range of genetic conditions. Her specialist interests include chromosomal disorders, rare genetic symptoms, and conditions with an underlying genetic cause.


Her sub-specialism is rare diseases of the skeleton. She has established multidisciplinary paediatric clinics in skeletal dysplasia offering a close monitoring and management service, and is an active researcher, working to develop and improve the diagnosis of severe skeletal conditions. She currently acts as the chief investigator for clinical trials in children with skeletal dysplasia, developing the diagnosis of genetic conditions and improving the accurate diagnosis of severe skeletal conditions. Her work is featured in many peer-reviewed publications and she has published extensively on various aspects of clinical genetics.


Dr Irving was a winner of the Genetic Healthcare Provider (GHP) Private Healthcare Awards 2019. In that same year, she published a book, The Human DNA Manual, offering insight into the origins, evolution and uses of genetic science. 

Clinics

The Portland Hospital
  • The Portland Hospital profile image

    The Portland Hospital - part of HCA Healthcare

    Central London, 205 - 209 Great Portland St. W1W 5AH,

    Medical insurances accepted

    I'm paying for myself

Credentials

Professional experience

  • 30 years of experience
  • Consultant Geneticist, HCA The Shard, London (present)
  • Consultant Geneticist, The Portland Hospital, London (present)
  • Consultant Geneticist and Honorary Reader in Clinical Genetics, Guy's & St Thomas' NHS Trust, London (present)
  • Joint head of service, Department of Clinical Genetics, Guy's Hospital (2014 - 2016)
View more

Subspecialties

  • Genetic counselling
  • Genetic diagnosis
  • Fetal medicine genetics
  • Skeletal dysplasia
  • Achondroplasia
  • Chromosome abnormalities
  • Genomic medicine
  • Genetic syndromes
  • Genetic variants
  • Genetic health risk reports
  • Carrier testing
  • Raised paternal age
  • Raised maternal age
  • Klinefelter syndrome
  • Aneuploidy
  • Cousins
  • Consanguinity
  • Infertility
  • Y chromosome
  • X chromosome
  • Karyotype
  • Mosaicism
  • Telephone consultations
View more

Professional memberships

  • Skeletal Dysplasia Management Consortium https://www.skeletaldysplasia.org/
  • UK Skeletal Dysplasia Group https://www.skeletaldysplasiagroup.org.uk/
  • PanThames Skeletal Dysplasia Group
  • The Royal Society of Medicine
View more

Education

  • Fellowship in Skeletal Dysplasia, The Royal Children's Hospital and Murdoch Children´s Research Institute (2006-7)
  • MD(Res) in Clinical and molecular studies in skeletal dysplasia, Kings College London (2014)
  • MRCPH, Membership of the Royal College of Paediatrics and Child Health (1999)
  • Senior House Officer, East London Paediatric Training Scheme (1998 - 2000)
  • MBBS, The London Hospital Medical College, University of London (1996)
  • BSc(Hons) in Genetics, University College London (1994)
  • FRCPCH, Fellow of the Royal College of Paediatrics and Child Health (2019)
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Teaching posts

  • Faculty Member, Skeletal Dysplasia Group Instructional Course (2012 - present)
  • Lecturer to undergraduate medical students, King's School of Medicine (2007 - present)
  • Postgraduate Training Lead, Clinical Genetics, Guy's Hospital (2005 - present)
  • Career insight and taster sessions in Clinical Genetics, Programme Coordinator (2004 - present)
View more

Positions in organisations

  • Trustee of the Royal Society of Medicine (2019-2023)
  • President, Medical Genetics section, The Royal Society of Medicine (2016-2019)
  • Chair, Ellison Cliffe Charitable Trust, The Royal Society of Medicine 
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Publications and conferences

  • Chromosomal anomalities:-
  • Microduplications at the pseudoautosomal SHOX locus in autism spectrum disorders and related neurodevelopmental conditions
  • Segmental paternal uniparental disomy (patUPD) of 14q32 with abnormal methylation elicits the characteristic features of complete patUPD14.
  • Deletion of the distal long arm of chromosome 10; is there a characteristic phenotype? A report of 15 de novo and familial cases.
  • A complex deletion-inversion-deletion event results in a chimeric IL1RAPL1-dystrophin transcript and a contiguous gene deletion syndrome
  • Developmental disorders and genetic syndromes:-
  • Prevalence and architecture of de novo mutations in developmental disorders. Deciphering Developmental Disorders Study
  • Clinical and genetic aspects of KBG syndrome
  • De Novo Mutations in CHD4, an ATP-Dependent Chromatin Remodeler Gene, Cause an Intellectual Disability Syndrome with Distinctive Dysmorphisms
  • Large-scale discovery of novel genetic causes of developmental disorders. Deciphering Developmental Disorders Study
  • Possible association between complex congenital heart defects and 11p15 hypomethylation in three patients with severe Silver-Russell syndrome
  • De novo mutations in MLL cause Wiedemann-Steiner syndrome
  • Paraspinal ganglioneuroma in the proband of a large family with mild cutaneous manifestations of NF1, carrying a deep NF1 intronic mutation
  • Infantile onset myofibrillar myopathy due to recessive CRYAB mutations
  • Collagen VI glycine mutations: perturbed assembly and a spectrum of clinical severity
  • Neonatal teeth in X-linked Opitz (G/BBB) syndrome
  • Genomic disorders:-
  • The genomic landscape of balanced cytogenetic abnormalities associated with human congenital anomalies
  • Skeletal dysplasia:-
  • Best Practices in Peri-Operative Management of Patients with Skeletal Dysplasia
  • Recurrent missense mutation of GDF5 (p.R438L) causes proximal symphalangism in a British family
  • Rodriguez acrofacial dysostosis is caused by apparently de novo heterozygous mutations in the SF3B4 gene
  • End-Stage Renal Disease in an Infant With Hajdu-Cheney Syndrome
  • Clinical utility gene card for: 3-M syndrome - update 2013
  • Serpentine fibula polycystic kidney syndrome is part of the phenotypic spectrum of Hajdu-Cheney syndrome
  • Clinical management of achondroplasia
  • Two novel COL2A1 mutations associated with a Legg-Calvé-Perthes disease-like presentation
  • Mutations in NOTCH2 cause Hajdu-Cheney syndrome, a disorder of severe and progressive bone loss
  • Clinical utility gene card for: 3M syndrome
  • Chondrodysplasia punctata: a clinical diagnostic and radiological review
  • Primary skeletal dysplasia as a major manifesting feature in an infant with congenital disorder of glycosylation type Ia
  • IFT80, which encodes a conserved intraflagellar transport protein, is mutated in Jeune asphyxiating thoracic dystrophy
  • Cancer Genetics:-
  • Breast cancer genetics: unsolved questions and open perspectives in an expanding clinical practice
  • Genetics of breast cancer
  • The Human DNA Manual: Understanding Your Genetic Code 
View more

Prizes and awards

  • Winner of the Genetic Healthcare Provider (GHP) Private Healthcare Awards  (2019)
  • Maroteaux Award for furthering the understanding of skeletal conditions (2011)
  • Ellison-Cliffe Foundation travelling fellow award, the Royal Society of Medicine (2006)
  • Guy’s and St Thomas’ Charity staff development award (2006)
View more

Languages spoken

  • English
Registration number: 4311733

Reviews

All reviews are from real patients and have been verified by our Customer Service department to ensure they meet our guidelines. Rules of the service

47 reviews

5.0

Review this doctor
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  • 12 December 2025

    P.J.

    Verified patient
  • 25 September 2025

    R.S.

    Verified patient
  • Wonderful doctor. very knowledgeable and a kind manner. She knew exactly how to help us. As someone whom also works in healthcare I was hugely impressed and very happy with the consultation. I would have no hesitation in recommending Dr Irving.
    4 July 2024

    S.E.

    Verified patient
  • I would highly recommend Dr. Irvin! We came from far for consultation with Dr. Irvin and we are very glad that we met her in our search for a high level specialist. Before&after consultation she is always in contact with us answering our questions and explaining her conclusions.
    14 May 2024

    K.S.

    Verified patient
  • Dr Melita took her time to understand and help us with our requests. We felt finally heard and understood we appreciate everything Dr Melita has done for us.
    13 March 2024

    A.B.

    Verified patient
  • Good doctor. Listening well, making me understand well her answer, explaining again if necessary. Kind and patient , highly recommended
    6 February 2024

    S.B.

    Verified patient
  • Dr Melinda Irvine was very approachable and professional, She was empathetic and ensured she had all the information at hand to understand our issues better. After our E-consultation, I felt at ease that our concerns were addressed seriously, and I felt her advice was exceptional.
    11 January 2024

    T.S.

    Verified patient
  • I was able to arrange an online appointment with Dr. Irving quite quickly. She was very friendly and took time to answer all my questions thoroughly, simply and in a caring manner. She followed up with a detailed report of the consultation including recommendations.
    20 December 2023

    N.K.

    Verified patient
  • Dr. Melita Irving has an awesome personality, she made me and my daughter feel very comfortable. Sometimes my daughter can get very playful and very active. But Dr. Melita was extremely patient, played & assessed her joyfully throughout the appointment. I am very grateful to her.
    11 December 2023

    L.P.

    Verified patient
  • Very reassuring and obviously hugely thorough and experienced.
    6 December 2023

    L.P.

    Verified patient
View all reviews

Treatments

The doctor is expert in

Achondroplasia

Developmental delay

Genetic disorders

Genetic testing

Skeletal dysplasia

The doctor also specialises in:

Aneuploidy

Chromosomal abnormalities

Consanguinity

DNA testing

Direct-to-consumer genetic testing

Genetic counselling

Genetic syndrome

Genetic testing results

Genomic medicine

Infertility

Frequently Asked Questions

What is Dr Melita Irving's specialty?

Dr Melita Irving is a consultant specialising in Clinical Genetics, with extensive experience in assessing and treating patients within this field.

Which conditions and treatments does Dr Melita Irving specialise in?

Dr Melita Irving is a clinical Geneticist who provides assessment and treatment for Achondroplasia, Skeletal dysplasia, Genetic testing, Genetic disorders and Developmental delay. During your consultation, you will be informed of the most suitable options following a personalised evaluation.

How many years of experience does Dr Melita Irving have?

Dr Melita Irving has 30 years of professional experience as a consultant clinical Geneticist, providing specialist assessment and treatment in this medical field.

What do patients say about Dr Melita Irving?

Patients give a rating of 5.0 out of 5 to Dr Melita Irving, a score considered excellent. This average is based on 47 verified patient reviews, reflecting the experience of those who have attended an appointment.

Are Dr Melita Irving's reviews verified?

Yes. All Dr Melita Irving's reviews come from verified patients who have attended either an in-person or an e-Consultation appointment. We use a system that ensures authenticity and prevents fake reviews. Some profiles may also display reviews from other platforms, which follow their own verification policies, with the source always clearly indicated.

Where does Dr Melita Irving practise?

Dr Melita Irving practices in the following locations:

  • Central London at 205 - 209 Great Portland St. W1W 5AH
  • Central London at 32 St Thomas Street, SE1 9BS
  • Central London at 27 Tooley St

In-person consultations are available at these locations as a Clinical Genetics.

How can I book an appointment with Dr Melita Irving?

You can book an appointment with Dr Melita Irving directly from this page by selecting the time that suits you best. Alternatively, you can call the phone number shown if you prefer personalised assistance.

Does Dr Melita Irving see NHS patients?

Many specialists featured on Top Doctors also hold NHS positions. However, appointments arranged for Dr Melita Irving through this platform are private, either self-pay or covered by private medical insurance.

Does Dr Melita Irving offer private appointments?

Yes, Dr Melita Irving offers private appointments for patients seeking flexible and direct access to a consultant clinical Geneticist.

Does Dr Melita Irving offer online consultations?

Yes, Dr Melita Irving offers online consultations. You can book an appointment directly from this page by selecting the date and time that suit you best. Personalised assistance is also available by calling the number displayed on this page.

Does Dr Melita Irving accept insurance?

At the moment, Dr Melita Irving offers consultations on a private, self-pay basis only.

What is Dr Melita Irving's availability?

Dr Melita Irving's availability depends on the appointment slots open at any given time. On this page, you can check current availability, and if no slots are shown, you can request an appointment or contact the practice directly.

What payment methods does Dr Melita Irving offer?

You can pay for your consultation with Dr Melita Irving using the following methods: Self-paying.

What languages does Dr Melita Irving speak?

Dr Melita Irving is a clinical Geneticist who offers consultations in English.

How is Dr Melita Irving selected to appear on this platform?

All doctors listed on Top Doctors, including Dr Melita Irving, undergo our rigorous selection process. Only one in five specialists meets the required standards to be included.
Discover Top Doctors' rigorous medical selection process.
The doctor, or where applicable the hospital or medical centre in which the doctor provides services, undertakes to keep the information relating to the prices of services published on their profile on the Top Doctors platform up to date at all times, ensuring that such prices correspond to those effectively charged to patients. In the event of any discrepancy between the published price and the price ultimately charged to the patient, the doctor and/or the relevant hospital or medical centre shall be solely liable towards the patient and towards Top Doctors for any claim or financial difference arising therefrom.

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The Portland Hospital - part of HCA HealthcareCentral London, 205 - 209 Great Portland St. W1W 5AH,
Payment methodSelf-paying
Face-to-faceFirst visit Clinical Genetics
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