


With age, there is a decrease in the effective function of the exocrine glands that affect the eyes, mouth, throat, etc.
If testosterone decreases or there are insufficient testosterone receptors, the gland begins to hypofunction. Women may begin to develop ocular dryness when they reach menopause as their androgens naturally decrease.
There are multiple drugs capable of producing ocular dryness due to their secondary exocrine hypersecretory effects including anxiolytics, antidepressants, sleeping pills and hypnotics, antiparkinsonians, antihistamines and diuretics.
Dry eye due to malnutrition or lack of vitamins was the most frequent cause of severe dry eye for millennia, and is still present in underdeveloped countries. In developed countries they are rare causes, and are usually produced by intestinal malabsorption (alcoholism, Crohn's disease, intestinal resections, etc.) or from diets lacking fats.
Infections of the lacrimal glands affect the aqueous glands that affect the mucous membrane that covers the eyeball.
Glands can be damaged physically or through contact with chemicals. The severity of dry eyes due to trauma varies greatly depending on the extent of the trauma.
There are many treatments, but they are not usually curative. The symptom is treated but often the root cause remains. Treatments that improve the quality of life of patients with dry eye can be changes to hygienic routine, artificial tears or eye drops, drugs that stimulate tear secretion and surgical techniques.