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All about chronic fatigue syndrome

Dr Margareta Griesz-Brisson
Written in association with: Dr Margareta Griesz-Brisson Neurologist in W1G Marylebone London
4.6 |

14 reviews

Sources: Top Doctors GB
Published: 18/03/2025 Edited by: Conor Lynch on 14/04/2025

Chronic fatigue syndrome (CFS), also known as Myalgic Encephalomyelitis (ME), is a complex and debilitating disorder characterized by extreme fatigue that lasts for at least six months and is not improved by rest. This condition affects millions of people worldwide, yet it remains poorly understood, often leading to misdiagnosis and stigma.

The hallmark symptom of CFS is profound fatigue that significantly impairs daily activities. Unlike typical tiredness, this fatigue is persistent and can be exacerbated by physical or mental exertion, a phenomenon known as post-exertional malaise.

 

Other common symptoms include sleep disturbances, cognitive difficulties (often referred to as "brain fog"), muscle pain, joint pain, headaches, and sore throat. The variability of symptoms can make diagnosis challenging, as they often overlap with other conditions. The exact cause of CFS is still unknown, but research suggests that it may involve a combination of genetic, environmental, and psychological factors.

 

Some studies indicate that viral infections or immune system dysfunction could trigger the onset of the syndrome. Additionally, stress and hormonal imbalances may play a role in its development. Diagnosis typically involves ruling out other medical conditions with similar symptoms since there are no definitive tests for CFS. Healthcare providers often rely on patient history and symptom assessment to make a diagnosis.

 

Currently, there is no cure for CFS; however, management strategies focus on alleviating symptoms and improving quality of life. Cognitive behavioural therapy (CBT) and graded exercise therapy have shown some effectiveness in helping patients cope with their condition. Lifestyle modifications, such as pacing activities and ensuring adequate rest, are also crucial.

 

Raising awareness about CFS is essential to reduce stigma and improve support for those affected. As research continues to evolve, there is hope for better understanding and treatment options for this challenging syndrome.

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