

Ozempic is an exciting new treatment for both diabetes and obesity. However, evidence is emerging that this drug may be contributing to tooth erosion. In this article, a cosmetic dentist, Dr Mark Hughes, explains how tooth erosion occurs, and the techniques used to correct it.

Tooth erosion is a progressive loss of the hard surface of the teeth, typically caused by acid attacking the enamel. In recent years, growing attention has been paid to the possible dental side effects of medications such as Ozempic, particularly as its use expands beyond diabetes management to weight loss. For individuals experiencing dental complications linked to Ozempic, modern restorative and cosmetic dental techniques can offer effective solutions for reconstructing damaged teeth and restoring oral health.
Ozempic (semaglutide) is a medication originally developed to help manage type 2 diabetes. It works by mimicking a natural hormone (GLP-1) that helps regulate blood sugar, slow gastric emptying, and promote feelings of fullness. More recently, Ozempic has been widely prescribed off-label for weight loss due to its appetite-suppressing effects. While the medication has shown impressive results in both areas, some patients have reported unexpected side effects, including changes in oral health.
One of the lesser-known effects of Ozempic is its potential impact on the mouth through increased acid reflux, dry mouth (xerostomia), and nausea-induced vomiting. Slower stomach emptying and reflux can raise acid levels in the oesophagus and mouth, while dry mouth reduces the natural buffering and cleansing effect of saliva. Together, these factors can expose teeth to higher levels of acid, leading to enamel erosion over time. Enamel, the hard outer layer of the tooth, once lost does not regenerate. Left untreated, erosion can result in sensitivity, pain, changes in tooth shape, and increased risk of decay and fracture.
Fortunately, various dental reconstruction methods are available to restore eroded teeth, depending on the extent of the damage. In cases of mild erosion, composite bonding may be used to rebuild lost enamel using tooth-coloured resin. This method is minimally invasive and often completed in a single visit. For more significant damage, porcelain veneers or crowns can provide both strength and aesthetic improvement. These options are designed to restore natural tooth shape and protect against further wear.
When erosion has affected the bite or multiple teeth, full-mouth rehabilitation may be recommended. This comprehensive approach often combines different treatments to rebuild the occlusion (bite) and restore proper function. As a cosmetic and restorative solution, it not only addresses structural issues but also enhances the appearance of the teeth, improving both comfort and confidence.
While reconstruction can restore the appearance and function of eroded teeth, it is equally important to address the underlying causes. For patients using Ozempic, this may involve working with their GP or specialist to manage side effects such as reflux or dry mouth. Dentists may recommend saliva substitutes, fluoride treatments, or tailored oral hygiene products to support enamel strength and reduce acidity in the mouth. Diet also plays a critical role – limiting acidic food and drink can help reduce further erosion. In some cases, using a nightguard can protect teeth from additional wear caused by grinding.
As the use of Ozempic continues to rise, both for diabetes and weight loss, awareness of its potential dental side effects is crucial. Tooth erosion, though gradual, can have a significant impact on oral health and quality of life. Thankfully, with the help of modern restorative dentistry, damaged teeth can be effectively rebuilt and protected. By combining clinical expertise with patient education and preventive strategies, dental surgeons can support long-term oral health for those affected by medication-related erosion.