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Activated clotting time (ACT)

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  • Activated clotting time (ACT)
Created: 26/03/2024
Edited: 26/03/2024
Written by: Conor Lynch

What is analysed in an ACT test?

The ACT measures the time it takes for blood to clot when heparin is added. It is particularly relevant in procedures where clot formation must be avoided, such as cardiac bypass surgery, coronary angioplasty, and dialysis.

What does the result mean?

The ACT result is expressed in seconds. A prolonged value indicates that blood is taking longer to clot due to the presence of heparin.

Why perform the analysis?

It is done to monitor heparin or other anticoagulant treatments. It is essential during surgical procedures like cardiac bypass, where high doses of heparin are administered.

When should this analysis be carried out?

During surgical interventions with high heparin doses, when heparin levels are so elevated that partial thromboplastin time (PTT) cannot be used for monitoring, and when a rapid result is needed for treatment control.

Is any sample required?

The determination is made from a sample of venous blood.

Is any preparation required?

No special preparation is needed for this test.

How is it used?

ACT is used to adjust heparin dosage during surgical procedures. It helps maintain a delicate balance between coagulation and bleeding. The normal range for ACT is 70 to 120 seconds without heparin and 180 to 240 seconds with heparin12345. Prolonged values may indicate excess heparin and bleeding risk. Very short values may suggest inadequate anticoagulation.

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