What is being analysed here?
The G6PDH test measures the levels of this enzyme in the blood. G6PDH protects red blood cells from certain toxic products derived from cellular metabolism.
What do the results mean?
Normal levels indicate adequate G6PDH activity in red blood cells. G6PDH deficiency can lead to red blood cell destruction and cause haemolytic anaemia.
Why is the analysis performed?
To diagnose G6PDH deficiency, a genetic disorder primarily affecting males. It is also performed to evaluate symptoms such as fatigue, pale skin, jaundice, rapid heart rate, shortness of breath, or dark-coloured urine.
When is this analysis carried out?
When G6PDH deficiency is suspected and in newborns with persistent unexplained jaundice or a family history of G6PDH deficiency.
What sample is required?
A venous blood sample is drawn. No special preparation is required for the G6PDH test.
How is it used?
Results guide the diagnosis and management of G6PDH deficiency. Normal values (adults): 8.6 to 18.6 units/gram of haemoglobin. Altered values: A value less than 10 per cent of normal indicates severe deficiency and haemolytic anaemia.