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Parathyroid hormone (PTH) analysis

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  • Parathyroid hormone (PTH) analysis
Created: 01/02/2024
Edited: 01/02/2024
Written by: Conor Dunworth

What is being analysed?

Parathyroid Hormone (PTH) levels in the blood are analysed. PTH is a crucial hormone that regulates calcium and phosphorus balance in the body.

 

What does the result mean?

The PTH result indicates the amount of PTH circulating in the bloodstream. Elevated or lowered levels can provide insights into various medical conditions, particularly those related to calcium metabolism.

 

Why is the analysis conducted?

PTH analysis is conducted to assess parathyroid function, identify disorders such as hyperparathyroidism or hypoparathyroidism, and diagnose underlying causes of abnormal calcium levels.

 

When to conduct the analysis?

PTH analysis is typically ordered when there are abnormalities in calcium levels, symptoms of calcium imbalance (fatigue, muscle weakness, bone pain), or suspicion of parathyroid dysfunction.

 

What sample is required?

A blood sample is required for PTH analysis. It is usually drawn from a vein in the arm.

 

Is any prior preparation necessary?

Fasting is not usually required. However, it's essential to inform the healthcare provider about any medications, supplements, or medical conditions that might affect the test.

 

What are the normal values?

Normal PTH levels typically range from 10 to 65 picograms per millilitre (pg/mL).

 

What do altered values mean?

Elevated PTH:

Hyperparathyroidism, which may indicate overactive parathyroid glands leading to excessive calcium release from bones.

Kidney disease or vitamin D deficiency.

Decreased PTH:

Hypoparathyroidism, signalling underactive parathyroid glands causing reduced calcium levels.

Surgical damage or removal of the parathyroid glands.

 

Reference Values for PTH Analysis:

Normal Range

Interpretation

10 - 65 pg/mL

Normal

Above 65 pg/mL

Elevated (possible hyperparathyroidism)

Below 10 pg/mL

Decreased (possible hypoparathyroidism)

Understanding PTH values is crucial in managing various conditions, ensuring prompt diagnosis, and tailoring effective treatment plans. If you have concerns about your PTH levels, consult with a healthcare professional for personalised guidance.

 

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