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What is a PSA test?

Mr Jeremy Crew
Written in association with: Mr Jeremy Crew Urologist in Oxford
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61 reviews

Sources: Top Doctors GB
Published: 03/02/2025 Edited by: Conor Lynch on 18/02/2025

A Prostate-Specific Antigen (PSA) test is a blood test used to measure the levels of PSA, a protein produced by the prostate gland. It is commonly used as a screening tool for prostate cancer and to monitor prostate health in men. The PSA test is particularly important for men over the age of 50 or those with a family history of prostate cancer, as they are at higher risk of developing the disease.

PSA is naturally present in the bloodstream, but elevated levels can indicate various prostate conditions, including benign prostatic hyperplasia (BPH), prostatitis (inflammation of the prostate), or prostate cancer. However, an increased PSA level does not always mean cancer is present. Other factors, such as age, recent ejaculation, prostate infections, or even certain medical procedures, can also cause a temporary rise in PSA levels.

 

The test is simple and involves drawing a small amount of blood, which is then analyzed in a laboratory. Results are typically measured in nanograms per milliliter (ng/mL), and while no specific PSA level guarantees the absence or presence of cancer, higher levels may prompt further investigation. If PSA levels are significantly elevated, doctors may recommend additional tests, such as a digital rectal exam (DRE), MRI, or prostate biopsy, to determine the cause.

 

While the PSA test is a valuable tool for detecting prostate abnormalities early, it is not a definitive diagnostic test for cancer. Some men with prostate cancer may have normal PSA levels, while others with high PSA may not have cancer. Therefore, doctors consider multiple factors, including medical history and additional tests, before making a diagnosis. Discussing the benefits and limitations of PSA testing with a healthcare provider helps men make informed decisions about their prostate health.

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