What is analysed?
Iron is an essential mineral and a key component of haemoglobin, a protein in red blood cells that transport oxygen and carbon dioxide.
The ferric metabolism test measures various markers related to the metabolism of ferric iron in the body, including:
- Serum iron: The amount of iron in the bloodstream.
- Ferritin: Ferritin is the storage form of iron in cells.
- Transferrin: Transferrin is the protein that binds to and transports iron around the body.
- Total iron-binding capacity (TIBC): TIBC is the maximum amount of iron that can be bound by transferrin.
- Unsaturated iron-binding capacity (UIBC): UIBC is the amount of transferrin in the blood that is not currently carrying iron.
What does the result mean?
The result indicates the concentration of iron in the body.
Why conduct the analysis?
The ferric metabolism test is conducted to help diagnose iron deficiency or iron overload (haemochromatosis), and to monitor iron treatment for iron-related disorders.
When to conduct the analysis?
The ferric metabolism test is conducted when low haemoglobin or haematocrit levels are detected, or when iron deficit or iron excess is suspected.
What sample is required?
A blood sample is used for the analysis of ferric metabolism. The blood is drawn from a vein, usually in the arm.
Is any prior preparation necessary?
Patients should fast for 12 hours before the blood sample is taken. In addition, patients should also inform a healthcare professional about any medications being taken, as they could affect results.
How is it performed?
The collected blood sample is sent to a laboratory, where it is analysed for various markers using immunoassays, colorimetry, or high-performance liquid chromatography (HPLC) techniques to quantify iron levels.
What are the normal values?
Typical reference ranges are listed below.
What does having altered values mean?
- Low concentrations: Low iron concentrations indicate iron deficiency.
- High concentrations: High iron concentrations indicate iron overload or recent iron supplementation.