What is being analysed?
Sickle cell anaemia is a genetic blood disorder affecting haemoglobin, the protein responsible for carrying oxygen. The test analyses the presence of abnormal haemoglobin, specifically HbS.
When is it requested?
The test is typically requested when there's a suspicion of sickle cell anaemia due to symptoms like fatigue, pain, or anaemia. It is also part of routine newborn screening in some regions.
Why undergo the analysis?
This analysis helps diagnose sickle cell anaemia, guiding healthcare professionals in designing an appropriate treatment plan and providing valuable information for genetic counselling.
When to undergo the analysis?
The test can be done at any age, but it is often performed early in life, especially for infants as part of newborn screening. For individuals with a family history, it may be recommended at specific milestones.
What sample is required?
A blood sample is required for the test.
Is any prior preparation necessary?
No specific preparation is required. However, it's advisable to inform the healthcare provider about any medications or supplements being taken.
How is it performed?
The blood sample is sent to a laboratory where it is analysed for the presence of abnormal haemoglobin. The process involves various techniques, including electrophoresis.
What are the normal values?
Normal values indicate the absence of abnormal haemoglobin. Results are usually reported as a percentage of HbS in the total haemoglobin.
|
Haemoglobin Type |
Normal Range |
|
HbS |
0% |
|
HbA |
95-98% |
|
HbA2 |
2-3% |
What does having altered values mean?
Altered values, indicating the presence of abnormal haemoglobin, suggest a diagnosis of sickle cell anaemia or carrier status. Further genetic testing may be recommended for confirmation.