Understanding and managing gout

Gout is a form of inflammatory arthritis characterised by sudden, severe attacks of pain, swelling, redness, and tenderness in the joints, most often the big toe.
These attacks, called gout flares, can happen unexpectedly and are incredibly painful. While it can affect any joint, the base of the big toe is the most common location.

What causes gout?
Gout is caused by a buildup of uric acid in the blood. Uric acid is a natural byproduct of the body's breakdown of purines, substances found in many foods. When the body produces too much uric acid or doesn't excrete enough, it can crystallize in the joints, leading to inflammation and pain.
Several factors increase the risk of gout:
- Diet: A diet high in purines (red meat, organ meats, seafood, sugary drinks) can contribute to high uric acid levels.
- Genetics: A family history of gout significantly increases the risk.
- Weight: Obesity is a major risk factor.
- Certain medical conditions: Conditions like kidney disease, high blood pressure and diabetes can increase the risk.
- Medications: Some medications, such as diuretics and low-dose aspirin, can increase uric acid levels.
- Alcohol consumption: Excessive alcohol intake can trigger gout flares.
Symptoms of a gout flare-up
A gout flare typically begins suddenly, often at night, with intense pain, swelling, warmth and redness in the affected joint. The joint may be so tender even the weight of bedsheets can be unbearable. Symptoms can last for a few days or even weeks if left untreated. Between flares, you may have no symptoms.
Diagnosis of gout
Your doctor will diagnose gout based on your symptoms, a physical exam, and possibly test results:
- Joint fluid analysis: A sample of fluid from the affected joint is examined under a microscope to identify uric acid crystals.
- Blood test: A blood test measures the level of uric acid in your blood. However, a normal uric acid level doesn't rule out gout, as some individuals can have gout with normal uric acid levels.
- Imaging tests (X-rays): These can help rule out other conditions and assess the extent of joint damage.
Treatment of gout
Gout treatment focuses on managing acute flares and preventing future attacks.
- Acute flare treatment: Treatment for a gout flare usually involves nonsteroidal anti-inflammatory drugs (NSAIDs), colchicine, or corticosteroids to reduce pain and inflammation. Your doctor will determine the best option for you based on your overall health and other medications you're taking.
- Long-term management (Preventing future flares): Long-term management aims to lower uric acid levels in your blood to prevent future attacks. This can involve:
- Lifestyle changes: This includes following a low-purine diet, losing weight if you're overweight or obese, limiting alcohol consumption, and increasing fluid intake.
- Medication: Your doctor may prescribe medications such as allopurinol or febuxostat to lower uric acid production.
Living with gout
Managing gout requires a proactive approach. Working closely with your doctor to develop a personalised treatment plan is essential. This plan will likely involve medication, lifestyle adjustments, and regular monitoring of your uric acid levels. Early diagnosis and treatment can help minimise the frequency and severity of gout flares and prevent long-term joint damage.

