How exactly does targeted therapy work?

Written by: Professor Hany Eldeeb
Published:
Edited by: Conor Lynch

In this article below, esteemed consultant medical and clinical oncologist, Professor Hany Eldeeb, provides us with an insightful guide on targeted therapy

What is targeted therapy?

Targeted therapy is a newer, more precise type of therapy that attacks cancer cells. It is a type of personalised medical therapy designed to treat cancer by interrupting unique molecular abnormalities that drive cancer growth. 

 

The drugs used in targeted therapy are designed to interfere with a specific biochemical pathway central to the development, growth, and spread of that particular cancer.

 

What types of cancer are treated with targeted therapy? 

These drugs are now a component of therapy for many common malignancies, including breast, colorectal, lung, and pancreatic cancers, as well as lymphoma, leukemia, and multiple myeloma

 

What happens during targeted therapy?

The action of targeted drugs can work to: 
 

  • Block or turn off chemical signals that tell the cancer cell to grow and divide
  • Change proteins within the cancer cells so the cells die
  • Stop making new blood vessels to feed the cancer cells
  • Trigger your immune system to kill the cancer cells
  • Carry toxins to the cancer cells to kill them, but not normal cells

 

What are the benefits of targeted therapy?

Target therapy is intended to kill cancer cells with as minimal an effect as possible on normal cells. Target therapy prolongs life considerably more when compared to empirical treatment, but this is only the case when there is a known specific target. 

 

 

Professor Hany Eldeeb is a highly proficient consultant medical and clinical oncologist who specialises in targeted therapy. If you have been diagnosed with cancer and are considering undergoing targeted therapy, make sure you contact Professor Eldeeb today to schedule in an appointment. You can do just that by visiting his Top Doctors profile.

By Professor Hany Eldeeb
Clinical oncology

Professor Hany Eldeeb is a highly accomplished consultant medical and clinical oncologist based in Milton Keynes and Oxford. He has a vast experience in different types of cancer sites that gives him unique experience in both complex cases and in metastatic cancer and more than one primary.

He treats breast cancer, lung cancer, brain cancer, prostate cancer, and cancer metastasis from different tumour sites. He has expertise in using target therapy, immunotherapy, chemotherapy, as well as gene sequenced-based therapy. In addition to that, he is also using state-of-the-art radiotherapy treatment including IMRT, IGRT, stereotactic radiotherapy and SABRT.

He is passionate about treating challenging cases, especially in cases that require outside-the-box thinking. Professor Eldeeb graduated in medicine from Mansoura University in 1989. Following this, he was appointed as an oncology registrar. He completed his MSc in 1995 and then undertook the roles of assistant lecturer and specialist in oncology.

He then pursued training at St Bart’s hospital in London and completed his MD in 2001. He has studied tirelessly throughout his career and was awarded a Professorship in Clinical Oncology in 2012. He has been working over the last 20 years as a consultant between Northampton, Milton Keynes and Oxford University Hospitals.

Alongside his focus on breast and lung cancer, Professor Eldeeb takes a keen interest in prostate cancer and brain tumours. He has undertaken many managerial roles in theses trusts and currently is the oncology lead at Milton Keynes and was a key member in establishing the newly opened cancer centre there. He currently leads a developing radiotherapy centre at Milton Keynes that is planned to open in 2024. 

Furthermore, he enjoys sharing his medical knowledge with others, working as an educational supervisor for postgraduate trainees in oncology at Milton Keynes and Oxford University Hospital as well as undergraduate student teaching for Buckingham medical school. Professor Eldeeb is a member of multiple organisations, including the prestigious Royal College of Radiologists, The European Society of Breast Cancer Specialists, The European Society for Medical Oncology, and European Society for Radiotherapy and Oncology .

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