All about gallstones

Written by: Mr Timothy Rees Worthington
Published: | Updated: 23/01/2019
Edited by: Cal Murphy

Gallstones are a problem that affects many people. We’ve all heard of them, but have you ever wondered what exactly gallstones are? Top surgeon Mr Tim Worthington is here to provide the answer, explaining the symptoms, causes, and possible complications of these painful little stones.

What are gallstones?

Gallstones quite literally are small stones that form from bile that's stored in the gallbladder.


What symptoms do gallstones cause?

Gallstones can cause pain, which tends to be situated in the upper abdomen. It can spread through to the back, up into the chest, and characteristically up to the shoulder. If stones move from the gallbladder into the bile ducts, they can also cause symptoms of jaundice, which is characterised by darkening of the urine, pale stools, and the whites of the eyes become yellow.


What causes gallstones?

In the western world, gallstones are generally made up of cholesterol and, to a lesser extent, bile and bile pigments. Because they're made of cholesterol, diet is often the cause of gallstones and people who have a high intake of saturated fat in their diet tend to develop stones. Stones can also be related to genetics, so gallstones often run in families, and I often see patients who have mothers, fathers and grandparents who suffered from gallstones in the past. Gallstones can also occur during pregnancy and pregnant women are particularly prone to development. They can also develop secondary to other medical conditions, such as Crohn's disease, where the absorption of bile from the gut is altered and stones form as a result of this.


Can gallstones cause complications?

Gallstones can cause a variety of complications. They can cause acute pain if they block the exit of the gallbladder and that can cause distension of the gallbladder and acute inflammation. In the long term, they can cause chronic inflammation due to the irritation of the gallbladder lining by the chemicals in the stones.

If gallstones move from the gallbladder into the bile ducts, they can cause symptoms such as jaundice, which is characterised by patients complaining of yellowing of the skin; they might notice that their urine becomes dark and their stools become pale. If gallstones block the bile ducts and cause an acute infection, patients can have a high fever and also develop jaundice.

If stones migrate further down the bile duct, they can block the pancreatic duct at the lower end of the bile ducts, which can cause acute pancreatitis. If a large stone were to move from the gallbladder into the gut, it can also cause intestinal obstruction characterised by acute pain and vomiting.

Finally, patients who've got long-standing gallstones that have been there for many years causing chronic inflammation, gallbladder cancers can develop as a result of gallstones.


By Mr Timothy Rees Worthington

Timothy Rees Worthington is a top general surgeon based in Guildford. He specialises in removing gallstones and hernias and treating the liver and pancreas. He is an expert in laparoscopic surgery, holding the position of Laparoscopic Tutor at the Minimal Access Therapy and Training Unit at the University of Surrey.

After graduating from the University of Birmingham, Mr Worthington was awarded the Royal College of Surgeons Simpson Research Fellowship and studied the biology of pancreatic cancer. He earned his MD in 2001, after which he underwent higher surgical training in London and undertook further specialist training at Flinders University, Adelaide, Australia. He became a consultant surgeon at University College Hospital, London in 2004, before later moving to the Royal Surrey County Hospital.

Mr Worthington leads the Hepatopancreaticobiliary Unit at the Royal Surrey County Hospital and University of Surrey in the development of minimally-invasive surgery for pancreatic and liver disease and is an acknowledged expert in the field. 

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