An expert's in-depth guide to IBS: Causes, symptoms and treatment

Written by: Dr Syed Shariq Hasan
Published:
Edited by: Conor Dunworth

In his latest online article, renowned IBS specialist Dr Syed Shariq Hasan offers his expert insight into irritable bowel syndrome. He explains in-depth the symptoms, causes, diagnosis and treatment of this condition.

 

What is Irritable Bowel Syndrome (IBS)?

Irritable bowel syndrome (IBS) is the most common illness among the ‘Disorders of Gut Brain Interaction (DGBI)’ formerly called ‘Functional gastrointestinal disorders’ [1]. It may be defined as;

‘A condition comprising a group of functional bowel disorders in which abdominal discomfort or pain is associated with defecation or a change in bowel habit with features of disordered defecation’ [2].

Although IBS does not pose serious health risks, it can significantly impact a person's quality of life and productivity.

 

What are some common symptoms of IBS?

The symptoms of IBS can vary from person to person, and individuals may experience them differently in terms of severity and frequency[3]. It is essential to note that the symptoms may come and go, and they can be triggered or worsened by various factors such as stress, dietary triggers, medical or surgical intervention and hormonal fluctuations.

The most common symptoms include:

  • Abdominal pain or discomfort (any site): Often relieved after a bowel movement.
  • Bloating: A feeling of fullness or tightness.
  • Distension: Increase in the abdominal girth.
  • Changes in bowel habits: This can include diarrhoea (IBS-D), constipation (IBS-C), alternating (IBS-A) or unclassified (IBS-U).
  • Changes in the form of stool:  Change in the appearance or consistency of stool.
  • Flatulence: Excessive wind may accompany other symptoms.
  • Mucus in stools: Sometimes, mucus may be present in the stool.
  • Incomplete evacuation: Feeling of not emptying properly.

 

However, there are some red flag symptoms as shown below that should not be ignored and warrant further investigations:

  • Nocturnal pain: Pain that awakens or interferes with sleep.
  • Diarrhoea: Clinical suspicion of organic disease (stool wt. >250g/day).
  • Rectal bleeding: Blood in the stools (visible or occult).
  • Weight loss: Sudden unintentional.
  • Fever: Without any cause.
  • Abnormal physical examination: Any abnormal finding during physical examination.

 

In addition, there may be certain non-colonic symptoms [4] such as:

  • Nausea/vomiting
  • Difficulty in swallowing
  • Early satiety

 

Some patients may also present with any of the following extra-intestinal symptoms alongside their gut problems:

  • Back pain
  • Headache
  • Thigh pain
  • Poor sleep
  • Fatigue/ lethargy
  • Bad breath
  • Urinary symptoms
  • Gynaecological symptoms

 

What are the Principal Causes of IBS?

The exact cause of IBS remains unclear, but several factors can contribute to its development. Some potential causes and triggers include:

  • Motility: It is a disorder of motility and the abnormal contractions can involve any part of the gut which may contract more intensely or slowly than usual, leading to changes in bowel movements.
  • Visceral sensitivity: The increased sensitivity of the nervous system in the gut leads to an increase in the severity of abdominal symptoms.
  • Inflammation: Previous inflammatory changes or the existence of current low-grade inflammation can lead to the abnormality of bowel function.
  • Infections: Gastrointestinal infection may either cause an exacerbation of existing IBS symptoms or could be a trigger for post-infective IBS.
  • Antibiotics: Some patients develop IBS symptoms usually after long-term or repeated use of antibiotics.
  • Dysbiosis: Dysbiosis is the imbalance between the host and intestinal microbiota caused as a result of gastrointestinal infections, bowel surgeries, dietary irregularity and excessive use of antibiotics.
  • Pelvis surgery: IBS may develop as a consequence of abdominopelvic or gall bladder surgery.
  • Genetic predisposition: IBS has been shown to run in some families thus indicating a genetic predisposition.
  • Dietary factors: Food sensitivities and eating disorders result in exacerbation of symptoms and also difficulties in managing the condition.
  • Psychological factors: Emotional stress, mental health problems, psychological trauma and a history of any form of abuse can exacerbate the symptoms of IBS.  

 

How is IBS diagnosed?

Diagnosing IBS involves a process of elimination, as there is no specific test for the condition. Doctors rely on the patient's medical history, symptoms, and physical examination to rule out other gastrointestinal disorders. Diagnostic tests, such as stool samples, blood tests, and imaging studies, may be performed to rule out other conditions [5].

 

What is the treatment of IBS?

The treatment of IBS involves pharmacological and non-pharmacological approaches.

Pharmacologic:

The pharmacological treatment depends on the IBS type and severity.

  • Antidiarrheal- For patients with diarrhoea-predominant IBS
  • Laxatives- For patients with constipation-predominant IBS
  • Antispasmodics- Smooth muscle relaxants for pain.
  • Antidepressants- Help manage bowel symptoms including pain

 

Non-pharmacologic:

Lifestyle changes:

Certain lifestyle changes can effectively manage IBS symptoms and improve overall well-being. Some helpful strategies include:

  • Dietary modifications: Identifying and avoiding trigger foods, eating smaller meals, and maintaining a balanced diet helps to manage the symptoms.
  • Stress management: Techniques like meditation, mindfulness, deep breathing exercises, and help reduce stress and its impact on IBS.
  • Regular exercise: Engaging in moderate physical activity can promote healthy bowel function and relieve symptoms.
  • Adequate hydration: Drinking plenty of water helps keep the digestive system functioning smoothly.
  • Probiotics: Some individuals find relief from IBS symptoms by taking probiotics to support gut health.

Brain-Gut Behavioural Therapies:

Brain gut behavioural therapies such as, ‘Gut Directed Hypnotherapy’ has been shown through extensive research to be very effective in the management and treatment of IBS [6-15]. The benefits have been shown to last long-term [16].

In addition to this cognitive behavioural therapy, psychotherapy psychodynamic interpersonal psychotherapy, expressive writing etc. are also used to manage symptoms of IBS [17].

 

Is there a connection between IBS and other gastrointestinal disorders?

IBS may have overlapping symptoms with other gastrointestinal disorders, making the diagnosis more challenging. Conditions such as inflammatory bowel disease (IBD), celiac disease, and gastroesophageal reflux disease (GERD) share some symptoms with IBS. Proper medical evaluation and testing are crucial to differentiate between these disorders and develop an appropriate treatment plan.

 

 

If you would like to book a consultation with Dr Syed Shariq Hasan, you can do so today via his Top Doctors profile. 

 

 

References:

1. Oka, P., Parr, H, Barberio, B, Black, CJ, Savarino, EV, Ford, AC, Global prevalence of irritable bowel syndrome according to Rome III or IV criteria: a systematic review and meta-analysis. . The Lancet Gastroenterology & Hepatology. , 2020.

2. Thompson WG, L.G., Drossman DA, Heaton KW, Irvine EJ, Müller-Lissner SA, Functional bowel disorders and functional abdominal pain. Gut, 1999.

3. Maxton DG, M.J., Whorwell PJ. , Ranking of symptoms by patients with the irritable bowel syndrome. . BMJ. , 1989 Nov 299(6708): p. 1138. .

4. Whorwell PJ, M.M., Creed FH, Roberts CT. , Non-colonic features of irritable bowel syndrome. Gut., 1986 27(1): p. 37-40.

5. NICE, Irritable bowel syndrome in adults: diagnosis and management National Institute for healthcare and excellence guidelines; , in CG61. 2008.

6. Miller V, C.H., Morris J, Hasan SS, Archbold S, Whorwell PJ. , Hypnotherapy for irritable bowel syndrome: an audit of one thousand adult patients. . Aliment Pharmacol Ther. , 2015 41(9): p. 844-55.

7. Vasant D, H.S., Cruickshanks P, Whorwell P. , Gut-focused hypnotherapy for children and adolescents with Irritable Bowel Syndrome. . Frontline Gastroenterology, 2020.

8. Hasan SS, W.P., Miller V, Morris J, Vasant DH. , Six vs 12 Sessions of Gut-focused Hypnotherapy for Irritable Bowel Syndrome: A Randomized Trial. . Gastroenterology, 2021. 160(7): p. 2605-2607.e3. .

9. Hasan SS, V.D., The Emerging New Reality of Hypnosis Teletherapy:A Major New Mode of Delivery of Hypnotherapy and Clinical Hypnosis Training. International Journal of Clinical and Experimental Hypnosis (In Press), 2023.

10. Hasan SS, P.J., Morris J, Whorwell PJ. , Skype hypnotherapy for irritable bowel syndrome: effectiveness and comparison with face to face treatment International Journal of Clinical and Experimental Hypnosis 2019.

11. Donnet AS, H.S., Whorwell PJ. , Hypnotherapy for irritable bowel syndrome: patient expectations and perceptions. . Therap Adv Gastroenterol., 2022 p. 15;15:17562848221074208. .

12. Noble H, H.S., Whorwell PJ, Vasant DH. , The symptom burden of Irritable Bowel Syndrome in tertiary care during the COVID-19 pandemic. Neurogastroenterology & Motility, 2022: p. 34:e14347.

13. Noble H, H.S., Simpson V, et al Patient satisfaction after remotely delivered gut-directed hypnotherapy for irritable bowel syndrome during the COVID-19 era: implications for future practice. BMJ Open Gastroenterology, 2022;: p. 9:e001039. .

14. Sasegbon, A., Hasan, S.S., Whorwell, P.J. and Vasant, D.H. , Experience and clinical efficacy of gut-directed hypnotherapy in an Asian population with refractory irritable bowel syndrome. JGH Open, 2022. 6: p. 447-453. .

15. Gonsalkorale WM, W.P., Hypnotherapy in the treatment of irritable bowel syndrome. Eur J Gastroenterol Hepatol., 2005. 17(1): p. 15-20. .

16. Calvert EL, H.L., Cooper P, Morris J, Whorwell PJ. , Long-term improvement in functional dyspepsia using hypnotherapy. . Gastroenterology. , 2002 123(6): p. 1778-85. .

17. Guthrie E, W.P., Psychotherapy and hypnotherapy in IBS. , in Irritable Bowel Syndrome: Diagnosis and Treatment, S.R. In: Camilleri M, eds., Editor. 2002, WB Saunders: London. p. 151–9.

By Dr Syed Shariq Hasan
Gastroenterology

Dr Syed Shariq Hasan is an accomplished physician and IBS specialist with a distinguished specialisation in irritable bowel syndrome (IBS) and gut-directed hypnotherapy /brain gut behavioural therapies, based in Manchester. With an extensive career spanning over 30 years, Dr Hasan has become a renowned expert in the field of functional bowel disorders also called disorders of brain gut interaction (DGBI).

As a skilled medical professional, he is committed to accurate diagnoses and evidence-based treatment approaches. Notably, Dr Hasan holds a special interest in gut-focused hypnotherapy, exploring innovative methods to enhance patient outcomes and improve their quality of life. He has achieved remarkable success in this area, further solidifying his reputation as a leading authority in the treatment of IBS.
 
Dr Hasan is also a specialist in psychosomatic medicine and helps patients manage stress, anxiety, low self-esteem, lack of confidence, insomnia, fears, and phobias. He has also contributed to the book ‘Teach Yourself to Sleep’ by Kate Mikhail to help people with sleep disorders. He has been a consultant for the Institute of Psycotrauma Pakistan and the Institute of Mind Sciences.
 
Dr Hasan pursued his medical studies at Dow University of Health Sciences, graduating with an MBBS in 1992. He chose to expand his knowledge by attaining a Master of Public Health MPH from Karachi University in 1997, as well as the membership of the College of Physicians and Surgeons of Pakistan (MCPS) in the field of family medicine. His interest in research drove him to undertake a PhD in medicine at The University of Manchester, where he contributed significantly to the advancement of medical knowledge in his field.
 
Beyond his clinical expertise, Dr Hasan plays an integral role in shaping future medical professionals. He currently holds the position of honorary clinical senior lecturer/associate professor in the Division of Diabetes, Endocrinology and Gastroenterology (DEG) at the University of Manchester, inspiring and educating the next generation of physicians. 

Additionally, Dr Hasan generously imparts his knowledge as a visiting faculty member at the Central Institute of Family Medicine in Pakistan, contributing to medical education and practice on an international level.
 
His commitment to advancing medical science extends to his research interests, evident in his extensive publication record and active participation in national and international conferences. Dr Hasan's research contributions have significantly enriched the understanding of IBS and related conditions, benefitting the global medical community.

Furthermore, Dr Hasan is a public health specialist and advocates for preventive health awareness and research in developing nations, exemplified by his role as the Founder of Healthwatch healthcare service since 1997 and being a consultant for Manchester Global Foundation since 2015. Through this initiative, he aims to create a positive impact on public health by promoting early detection and intervention strategies. He generously volunteers his time and expertise demonstrating his commitment to improving healthcare accessibility and equity.

His work has received recognition and acclaim in the media both nationally and internationally.

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