Inflammatory bowel disease: Symptoms, diagnosis and treatment

Written by: Professor Lee Dvorkin
Published:
Edited by: Sophie Kennedy

Inflammatory bowel disease can cause a range of symptoms that greatly affect a person’s quality of life. Fortunately, with careful management, targeted treatment helps many patients to find relief from their symptoms. In this informative article, highly respected consultant colorectal and general surgeon Professor Lee Dvorkin shares his expert insight on the most common symptoms of inflammatory bowel disease, as well as the diagnostic process and various approaches to treatment.

What is inflammatory bowel disease (IBD)?

Inflammatory bowel disease is the name given to two main diseases of the bowel; ulcerative colitis and Crohn’s disease. They are different diseases, but both cause the bowel to become inflamed and lead to several symptoms. If the disease becomes severe, medical treatment with drugs and occasionally surgery is needed.


What are the symptoms of IBD?

Symptoms vary but include diarrhoea with urgency (having to rush to the toilet), mucus and blood from the bottom, tummy pain and weight loss. In children, delayed growth can occur.


How is IBD diagnosed?

Once the diagnosis is suspected, the doctor will perform a number of tests that will include a stool sample called calprotectin. This looks at whether the bowel is inflamed. Scans may also be needed to check the area of bowel that is affected.

However, the diagnosis is most commonly made by colonoscopy (a camera test in the bowel). Tissue samples can be taken of the bowel and, together with the other test results, usually allows the doctor to make a diagnosis. Sometimes, the diagnosis can be difficult to make and it may not be possible for the doctor to know whether this is colitis or Crohn’s disease.


What causes IBD?

The exact cause is unknown but there appears to be an abnormal immune response to certain environmental factors that lead to the bowel inflammation. There is also a genetic component with a higher chance of having IBD if a close relative also has it.


How is IBD treated?

Treatment depends on how severe the symptoms are and which part of the bowel is affected, so it may be different for each patient. In general, we treat IBD with dietary changes and various medications (including anti-inflammatory drugs, immune modulators, biological drugs and steroids). In severe cases, surgery is needed to remove the affected bowel. Many patients with Crohn’s disease get problems around their bottom and surgery is often needed for this.


Is there a cure for IBD?

There is no cure for Crohn’s disease. The aim of the treatment is to get the disease into remission for as long as possible. Once in remission, the patient’s symptoms will settle and sometimes ongoing medication is not needed.

For others, it may be more difficult to achieve remission and stronger medication or even surgery may be needed. Ulcerative colitis is usually controllable with medication but if this doesn’t work, it can be cured with surgery. Surgery involves removing the whole large bowel which is a major procedure and only recommended if all medicines fail.




If you are concerned by symptoms of inflammatory bowel disease or are seeking effective treatment for your condition, you can schedule a consultation with Professor Dvorkin by visiting his Top Doctors profile.

By Professor Lee Dvorkin
Colorectal surgery

Professor Lee Dvorkin is a leading and well-respected consultant colorectal and general surgeon based in London.

Professor Dvorkin specialises in all aspects of benign and malignant bowel diseases including bowel cancer and inflammatory bowel disease. His clinical practice also includes the investigation and management of gastrointestinal problems, such as irritable bowel syndrome (IBS), inflammatory bowel disease, diverticular disease, abdominal pain and all common anal conditions (rectal bleeding, haemorrhoids, fissures and anal fistulae). He is formally accredited in colonoscopy and gastroscopy and undertakes laparoscopic (keyhole) surgery for gallstones, appendicitis, hernias and bowel cancer.
He practices privately at The Hospital of St John & St Elizabeth Hospital, The Wellington Hospital, The Hendon Hospital and The Cavell Hospital, while his NHS base is the North Middlesex University Hospital NHS Trust.
Professor Dvorkin holds an ​MBChB from the University of Leeds and the FRCS from the Royal College of Surgeons. He completed his basic surgical training in Wessex and after undertaking a period of research at The Royal London Hospital, was awarded his MD by the University of London. His research focused on pelvic floor disorders and has been presented both nationally and internationally. Professor Dvorkin continues with his surgical research and to publish numerous original works. 

Professor Dvorkin's higher surgical training took place in London and was completed in 2010. He then undertook an 12-month fellowship and a six-month laparoscopic colorectal fellowship at St Marks Hospital, which is internationally renowned for the treatment of bowel diseases.
He has held and continues to hold various senior academic and educational roles in the NHS and enjoys training the next generation of surgeons as director of an RCS Senior Clinical Fellowship programme. He is one of only a few colorectal surgeons in England to hold such a position, and he is also an honorary senior lecturer at University College Hospital. 

Professor Dvorkin is a member of various professional organisations including the Association of Coloproctology of Great Britain and Ireland (ACPGBI), the Royal College of Surgeons of England and the General Medical Council. 

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