Breast cancer: Can losing weight bolster treatment and improve quality of life?

Written by: Dr Shiroma De Silva-Minor
Published: | Updated: 27/03/2024
Edited by: Conor Lynch

In this article below, esteemed consultant medical and clinical oncologist Dr Shiroma De Silva-Minor outlines the various benefits of losing weight for breast cancer patients. 

 

What are the main health benefits of losing weight for breast cancer patients?

As a breast oncologist, I am aware of numerous health benefits that weight loss can provide for breast cancer patients. Here are some potential benefits:

 

  1. Reduced risk of cancer recurrence: Obesity is associated with an increased risk of breast cancer recurrence and mortality. Weight loss may help reduce this risk by reducing the production of oestrogen, which can fuel the growth of hormone receptor positive cancers in particular.  
  2. Improved response to cancer treatments: Some studies have suggested that overweight and obese breast cancer patients may not respond as well to certain cancer treatments. For example, anti-oestrogen therapy, which is commonly used to treat hormone receptor-positive breast cancer, may be less effective in obese patients. Obesity is associated with higher levels of circulating oestrogen, which can promote the growth of hormone receptor-positive breast cancer cells. Research also suggests that drug metabolism and absorption rates may be different in obese patients.  Weight loss may improve the effectiveness of these treatments and improve overall outcomes.
  3. Improved cardiovascular health: Weight loss can reduce the risk of cardiovascular disease, which is a leading cause of death in breast cancer survivors, especially as some treatments for breast cancer such as anthracycline chemotherapy and radiotherapy (particularly to the left breast or chest wall) can increase risk of heart disease. Other cardiovascular disease risk factors, such as high blood pressure and high cholesterol, can also be improved with weight loss.
  4. Improved quality of life: Weight loss can improve overall quality of life by reducing fatigue, improving mood, and increasing energy levels. This can be especially important for breast cancer patients, who may experience fatigue and other side effects of cancer treatment.
  5. Reduced risk of other health problems: Obesity is associated with an increased risk of many chronic health problems, such as Type 2 diabetes, arthritis, and sleep apnoea. Weight loss can reduce the risk of these problems and improve overall health.

 

 

Is a crash diet or sudden weight loss advisable for breast cancer patients?

It's important to note that weight loss should be approached in a healthy, sustainable way, with realistic goals, and in conjunction with discussions and support from your doctor. Crash diets and rapid weight loss can be harmful and may not provide long-term benefits or be sustainable. A doctor or registered dietitian can help develop a safe and effective weight loss plan for breast cancer patients.

 

 

 

To book an appointment with Dr De Silva-Minor, simply visit her Top Doctors profile today. 

By Dr Shiroma De Silva-Minor
Medical oncology

Dr Shiroma De Silva-Minor is an accomplished and experienced consultant breast oncologist who specialises in breast cancer (both male and female), breast screening, chemotherapy, radiotherapy, immunotherapy, intraoperative radiation therapy, inflammatory breast cancers, HER2 positive disease, triple-negative breast cancers and breast cancer in pregnancy.

Dr De Silva-Minor oversees the entire (non-surgical) breast cancer pathway so she can advise on all aspects of treatment, including genetic counselling and testing, systemic (chemo) therapy, radiotherapy, and lifestyle factors in optimising health and minimising disease recurrence. Dr De Silva-Minor is currently practising privately, at the London-based Cromwell Hospital, as well as at GenesisCare Oxford, at The Chiltern Hospital, and as an NHS Consultant at the Oxford University Hospitals NHS Foundation Trust, Oxford.

Dr De Silva-Minor, whose clinical expertise is in the treatment of early and recurrent breast cancer, notably obtained her first medical qualification in 1995, with her medical doctorate from the prestigious Cardiff-based University of Wales College of Medicine. In 1999, Dr De Silva-Minor was awarded the membership of the Royal College of Physicians (UK). Dr De Silva-Minor pursued her specialist oncology training at several centres of oncological excellence in London, including The Middlesex Hospital, The Royal Free Hospital, as well as The Royal Marsden Hospital, amongst others.

In 2003, Dr De Silva-Minor was awarded the fellowship of the Royal College of Radiologists and was also recognised as a clinical oncology specialist on the General Medical Council's register in 2007. Dr De Silva-Minor has been a consultant oncologist since 2007 and was appointed as a substantive consultant oncologist by the Oxford University Hospitals NHS Foundation Trust in 2008.

Dr De Silva-Minor has published extensively in peer-reviewed journals. During a fellowship in head and neck radiation oncology at The Princess Margaret Hospital in Toronto, Canada, Dr De Silva-Minor was awarded the Prize for Academic Excellence by the Princess Margaret Hospital and the University of Toronto for her research into the use of PETCT scans (Positron Emission Tomography) when identifying head and neck tumours for treatment with radiotherapy. Dr De Silva-Minor is a member of the breast cancer expert panel for the National Institute of Health and Clinical Excellence (NICE), updating clinical guidelines on breast cancer management.

Dr De Silva-Minor is also collaborating on a metanalysis with the Early Breast Cancer Trialists' Collaborative Group (EBCTCG) to bring together the research on radiotherapy clinical trials to better understand how to optimally treat breast cancer patients with radiotherapy. Dr De Silva-Minor is a member of the Advisory Board on Cancer in Pregnancy (ABCIP), an international panel of experts in managing breast cancer in pregnancy. Dr De Silva-Minor is a passionate advocate for empowering her patients to be involved in their management decisions. Treatment is completely bespoke to individual patients, their specific tumour subtype, taking into consideration the individual's beliefs, wishes and personal circumstances.

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