Expert insights on HoLEP: Effective prostate treatment for lasting results

Written by: Mr Nkwam Michael Nkwam
Published:
Edited by: Sophie Kennedy

In this informative article, we hear from esteemed consultant urological surgeon Mr Nkwam Michael Nkwam on holmium laser enucleation of the prostate, or HoLEP, a cutting-edge, minimally invasive surgical technique for the treatment of prostate problems. The revered specialist details how advanced laser technology is used to effectively treat bothersome urinary symptoms, particularly for larger prostates. Mr Nkwam also discusses safety, recovery, and the long-term success rates which afford lasting relief and improved quality of life for men suffering from prostate symptoms.

What is HoLEP?

HoLEP stands for holmium laser enucleation of the prostate. It is a minimally invasive, specialist surgical technique whereby a fine laser fibre is used to peel the prostate away from its outer shell or capsule.


Why would someone require HoLEP?

The HoLEP procedure is, one of if not, the most effective form of bladder outlet surgery there is and lends itself very well to prostates of all sizes.

Men who have bothersome urinary symptoms such as poor flow, dribbling and hesitancy, and of course men who are unable to pass urine at all without the aid of a catheter, have a condition called benign prostatic hypertrophy (BPH). These men would benefit from the HoLEP procedure.

This highly effective laser operation comes into its own for really big prostates (i.e. greater than 80cc in volume). This is because due to the large size of such prostates, standard techniques such as TURP may struggle to remove enough prostate tissue to improve a man’s symptoms sufficiently. Furthermore, if symptom improvement is achieved, they invariably return after some time.


Is HoLEP considered major surgery?

No, HoLEP is a minimally invasive procedure for the treatment of men with BPH. It is considered to be a very safe procedure which can be performed under a general anaesthetic (patient asleep) or a spinal anaesthetic (patient awake but numb from the waist down) and can take anywhere from 45 minutes to three hours to complete depending on the size of the prostate. However, almost all patients are home the day after surgery, catheter-free!


What are the advantages and disadvantages of HoLEP?

The advantages of HoLEP include the ability to deal with prostates of any size. It offers the greatest improvement in symptom relief and urinary flow rate.

Amazingly, only about one per cent of men require a second surgical procedure to improve their symptoms at 10 years, whereas this figure can be as high as fifty per cent with other techniques.

Side effects are much like other surgical prostate procedures and include the following:

Common

  • temporary mild burning sensation on passing urine
  • bloodstained urine
  • retrograde ejaculation

Uncommon

  • temporary short term loss of urinary control - which can be improved with pelvic floor exercises

Rare

  • bleeding requiring blood transfusion or reoperation


How long do the results of HoLEP last? Can the prostate grow back?

Due to the completeness of the enucleation technique, minimal prostate tissue is left behind as it is all peeled off from the prostate capsule. This means there is very little chance for the prostate to grow back and cause recurrence of urinary symptoms. Hence, the results of the HoLEP surgery last up to 10 years in 99 per cent of men.




If you are considering undergoing HoLEP treatment or are experiencing troublesome urinary symptoms, you can schedule a consultation with Mr Nkwam by visiting his Top Doctors profile.

By Mr Nkwam Michael Nkwam
Urology

Mr Nkwam Michael Nkwam is a highly respected consultant urological surgeon based in London. He is renowned for his expertise in benign prostate hyperplasia (enlargement), prostate cancer diagnostics and Holmium laser (HoLEP). He additionally specialises in kidney stones, haematuria (blood in the urine) and vasectomy.

After obtaining a bachelor’s degree with honours, Mr Nkwam qualified in medicine from St. George’s, University of London in 2007. He completed his further surgical training in the West Midlands and was awarded membership of the Royal College of Surgeons of England in 2010. Mr Nkwam undertook specialist higher surgical training in urology in the East Midlands training programme and was appointed as a Fellow of the Royal College of Surgeons’ Urology section in 2017. Following this, he completed a twelve-month fellowship based at Luton and Dunstable University Hospital NHS Trust specialising in Holmium laser enucleation of the prostate (HoLEP) and endourology. Having gained invaluable insight into this form of treatment, he successfully performed the first HoLEP procedure at King’s College Hospital, London in 2020. With wide ranging expertise and experience in endourology, general urology and urological oncology, Mr Nkwam is regarded as a leading surgeon in his field. He sees private patients at HCA UK at The Shard, Chelsfield Park Hospital, the Shirley Oaks Hospital and the London Circumcision Centre.

Additional to his clinical responsibilities, Mr Nkwam provides essential training for GPs on a range of important areas of urology, including updates in the management of kidney stones, benign prostate hyperplasia and men’s health, amongst others. His numerous academic papers are published in revered peer-reviewed journals and he has presented his work at various key national and international conferences in his field.

Throughout his esteemed career, the excellence of Mr Nkwam’s work has been recognised with numerous awards, including ‘Best Poster in Session’ prizes, awarded by the European Association of Urologists in 2017 and the British Association of Urological Surgeons in 2018. That same year, Mr Nkwam was also the Ian McCallum Research Prize winner. He is a member of a number of key professional bodies, including British Urology Researchers in Surgical Training (BURST) and the British Association of Urological Surgeons (BAUS).

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