What is Gamma Knife and how does it work?

Written by: Mr George Samandouras
Published: | Updated: 13/03/2023
Edited by: Conor Lynch

In this article below, incredibly well-regarded and experienced consultant neurosurgeon, Mr George Samandouras explains what Gamma Knife is, outlines the associated benefits, before listing some of the risks involved.

What is Gamma Knife and how does it work?

Gamma Knife is a highly focused delivery of radiotherapy. It is typically performed during a day visit and is used as a treatment option for a number of benign and malignant brain tumours mainly. With Gamma Knife treatment, there is no need for repeated weekly treatments.

 

The process involves four steps: application of a frame resembling a helmet, a high resolution and detailed MRI brain scan with the frame on, visualisation, planning and targeting of the lesion(s) using an advanced planning software, and finally, the delivery of treatment using one of the latest Gamma Knife models that resembles a scanner.

 

What are the benefits of using Gamma Knife for brain metastases treatment?

Gamma Knife can be used for patients that have more than one lesion either on one or both sides of the brain. Lesions that are deep in the brain or close to very sensitive structures can be targeted effectively with Gamma Knife. 

 

How effective is Gamma Knife in treating brain metastasis compared to other treatments?

Following open surgery for large, single metastases, Gamma Knife is now used to boost the surgical cavity, which means that recurrences are significantly delayed.

 

What are the risks and side effects of Gamma Knife treatment for brain metastasis?

Although rare, side effects can occur. The main ones include infection or bruising of the scalp from the pin sites and local brain swelling. Rarer risks include haematoma, stroke, or seizures. Patients will not be allowed to drive for a month following Gamma Knife.

 

Is Gamma Knife treatment suitable for all patients with brain metastasis?

This depends on the number of brain lesions, the size, and location of each lesion, the primary cancer, the severity and spread of the primary cancer, and how well the patient feels and performs in daily activities.

 

To consult further with Mr George Samandouras, simply head to his Top Doctors profile today.

By Mr George Samandouras
Neurosurgery

Mr George Samandouras is a world-renowned Consultant Neurosurgeon and a respected authority in complex brain tumour surgery. His practice primarily operates at the National Hospital for Neurology and Neurosurgery in Queen Square, London, which is part of the University College London Hospitals (UCLH) NHS Foundation Trust, regularly ranked among the top neurosurgery hospitals in the world and being a part of the largest Academic Health Science Centre in Europe, UCL Partners. He also provides treatments to patients at the world-renowned Queen Square (Gamma Knife) Radiosurgery Centre.
 
Mr Samandouras specializes in managing various domains of complex brain tumours, including gliomas in critical parts of the brain, intraventricular tumours, posterior fossa, fourth ventricle and brainstem tumours, and pineal region tumours. With more than 30 years of experience, Mr Samandouras works alongside with a skilled multidisciplinary team of highly specialized professionals, including neuroradiologists and MRI physicists who report on functional and multiparametric neuroimaging, specialized neurologists, intraoperative neurophysiologists, neuropsychologists, speech and language therapists, and physiotherapists.
 
Beside the impressive work experience, Mr Samandouras has a vast amount of published original research and has received multiple Clinical Excellence awards.
 

View Profile

Overall assessment of their patients


  • Related procedures
  • Chronic headache
    Neuropathic pain
    Epilepsy
    Alzheimer's disease
    Movement disorders
    Transient ischaemic attack (TIA)
    Trapped nerve
    Scoliosis
    Spine fracture
    Rhizotomy
    This website uses our own and third-party Cookies to compile information with the aim of improving our services, to show you advertising related to your preferences as well analysing your browsing habits. You can change your settings HERE.