Understanding IVF treatment

Written by: Professor Nazar Amso
Published: | Updated: 24/06/2024
Edited by: Sarah Sherlock

If a woman or a couple are having troubles conceiving, they may turn to undergoing in vitro fertilisation (IVF) treatment. It is commonly known, but what else should we know about this treatment option? To help us understand more and answer important questions, expert consultant in assisted reproductive medicine Professor Nazar Amso explains all about IVF in this article.

 

in vitro fertilisation

 

What are the five steps of IVF?

The five steps of IVF are:

 

  1. Ovarian stimulation for growing follicles containing eggs involving different types of subcutaneous injections, one type to stimulate the follicular growth and one type to stop the eggs from being released prematurely.
  2. Transvaginal ultrasound-guided egg collection which involves passing a very fine needle through the vagina into the ovaries, usually under conscious sedation and more rarely under general anaesthetic.
  3. In vitro fertilisation of the eggs with sperm, or in cases of abnormal sperm, this can be replaced by the intracytoplasm sperm injection (ICSI).
  4. Transfer of the embryo inside the womb, ideally one embryo at a time should be transferred to avoid multiple pregnancy, which are dangerous for mum and babies.
  5. Attaching of the embryo to the lining of the womb, so called implantation.

 

 

Who is a good candidate for IVF and why?

Good candidates are generally young women with good egg reserve and a healthy womb. Women with tubal infertility have a better prognosis, as well as women who have conceived previously.

 

 

How long does IVF take from start to finish?

Depending on the stimulation, protocol can range between four and six weeks up until the stage of embryo transfer, then there will be two additional weeks to wait for the pregnancy test.

 

 

What are the disadvantages of IVF?

The main disadvantages of IVF include:

 

  • Risk of poor response to the drugs, meaning a low egg production or premature release of the eggs.
  • Overreaction to drugs, also known as ovarian hyper stimulation syndrome (OHSS), which very rarely could be life-threatening.
  • Injuries or infection during the eggs collection surgery
  • Failed fertilisation or arrest of the embryo during culture
  • Multiple pregnancy
  • Ectopic pregnancy (outside the womb)
  • Miscarriage

 

 

What advice would you give to women or couples undergoing IVF?

The best advice I’d give is to relax, be healthy, stop smoking, maintain a healthy weight, take supplements, and have the COVID-19 vaccination. I’d also advise having peer-to-peer support through social media, in addition to alternative remedies, such as acupuncture or reflexology which might help.

 

 

If you are considering having IVF treatment or would like more information, you can go to Professor Nazar Amso's and schedule a consultation.

By Professor Nazar Amso
Obstetrics & gynaecology

Professor Nazar Amso is a leading consultant obstetrician and gynaecologist currently practicing at Cardiff-based Oak Tree Clinic and Spire Cardiff Hospital, as well as St Joseph's Hospital, Malpas, Newport. He specialises in minimal access hysteroscopic and laparoscopic surgery, fertility investigations, treatments, adolescent gynaecology and joint clinics for paediatric care.

He qualified in 1974 from The College of Medicine at The University of Baghdad, in Iraq. After residency training at a number of teaching hospitals in Baghdad, Professor Amso chose to specialise in obstetrics and gynaecology. He studied at The University of Wales College of Medicine and The University Hospital of Wales, where he has established national and international clinical and research collaborations. 

His professional career journey in the UK began in 1981 and progressed in training posts from West and East Sussex, then later London and Newcastle Upon Tyne. He also undertook research between 1987-1991 at The Royal Free Hospital, London, which culminated in a consultant obstetrician and gynaecologist post at Gateshead.

Professor Amso's clinical practice has since focused on developing new and innovative approaches to service delivery for benign gynaecology. He set up the first ultrasound-based one-stop menstrual disorders clinic in Wales and introduced new treatments such as non-surgical interventions for fibroids and balloon endometrial ablation for menorrhagia. Ultrasound has been the passion of Professor Amso ever since he was a junior trainee. He pioneered the ovarian cancer screening trial in Cardiff and undertook many of the advanced scans. He also provided advice and counselling for the trial's volunteers.

Following Professor Amso's retirement from Cardiff University, he shifted his focus to his interest in education and incorporated limited companies to establish educational partnerships with other like-minded organisations and deliver remote/distance learning medical education in skills-focussed specialties for the UK and the rest of the world. 

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