Diabetic foot is a set of complications of vascular and nervous conditions that affects patients with chronic diabetes. The effect of irregular blood sugar levels on the vascular system may lead to arterial blockages that impede blood supply to the feet and in severe cases can cause gangrene. On a neurological level, the effect can be on a motor skill or sensory level. The sensation for the patient is the feeling of wearing a tight or excessive cold or heat sock, and the loss of muscle mass at foot level. Both causes, vascular and neurological, can result in of neuropathic diabetic foot ulcers, which can often be complicated by infection. A diabetic foot is often very delicate and vulnerable to discomfort when wearing shoes, although in many patients the symptoms are painless.