How is treatment for head and neck cancer improving?

Written by: Mr Peter Rhys-Evans
Published:
Edited by: Nicholas Howley

Leading ENT surgeon Mr Peter Rhys-Evans , founder and chairman of Oracle Cancer Trust, provides an insight into the field of head and neck cancer treatment, the incredible progress we’ve made over the last 40 years, and what patients can expect in the future.

Head and neck cancer is one of the major forms of cancer, accounting for 7-8% of all cancers in the UK. In other countries, this figure is even higher. In Asia, for example, around 30-40% of cancers occur in the head and neck, possibly because of the widespread practice of chewing tobacco, smoking cheap cigarettes and a poor diet. Worldwide, head and neck cancer causes 300,000 deaths every year.

Despite its prevalence, head and neck cancer seems to get far less attention than breast, colon, lung or prostate cancer. Perhaps this is because we are really talking about 30 different types of cancer, all lumped under one banner. Head and cancer can include cancer of the mouth, tongue, nose, ear, larynx, and the thyroid gland – and each one is unique in their symptoms and treatment. It isn’t something you can explain easily at a fundraising event.

Treatment for head and neck cancer: past and present

The key challenge with treating head and neck cancer is that it is so visible. It can affect our breathing, our swallowing, speech, senses, and our appearance. This means that when we look at improving treatment for people with head and neck cancer, we’re not just aiming for better cure rates – our challenge is to restore function and quality of life.

Just 30-40 years ago, treatment for head and neck cancer was primitive. If you survived the treatment, that was a success. Unfortunately many people were left with disfiguring scars, voice and swallowing problems, deafness, or loss of sight.

Since then, we’ve come a long way in restoring function and quality of life to patients. We are now able to reconstruct the voice mechanism to restore speech within three weeks after surgical removal of the voice box. Immunotherapy has become a key part of treatment for some types of cancer and advances in radiotherapy mean we can target tumours more effectively with reduced side effects.

We’ve also come far in terms of diagnosis and awareness. For example, we have seen a decrease in smoking-related mouth cancer among the UK population due to successful public health campaigning. More recently, we were successful in persuading the UK government to introduce the HPV vaccine to teenage boys, as well as girls – a key step in the fight against tonsil cancer.

The future of head and neck cancer

Despite these advancements, too many patients still suffer from speech, eating, or breathing difficulties following treatment, so we have improvements to make in this regard. Treatment must also adapt to the changing “face” of head and neck cancer – with more patients who are younger and presenting with tonsil cancer in association with the human papilloma virus (HPV).

Because we receive no money from the NHS for research, Oracle Cancer Trust was set up in 2001, since when we have raised over £6 million and are now the largest head and neck cancer charity in the UK. We are researching a range of ways to improve treatment for head and neck cancer, from robotic surgical techniques to viral therapies and new techniques in radiotherapy, aimed at targeting cancer cells without damaging the surrounding tissue. Our broader aim is to link up research efforts across the country and multiply our collective impact.

It is clear that momentum is building and I am confident we will continue to make great strides in our treatment of patients and ultimately minimise the impact of head and neck cancer on quality of life.

If symptoms and diagnosis are made early, there is an 80-90% chance of cure, but it is important that patients are treated in recognized head and neck cancer centres where cure rates are significantly better than national statistics. It is important to remember that these statistics are historical and they do not necessarily reflect your prospects today. Leading cancer centres are constantly striving to improve survival rates and outcomes and to reduce the adverse side effects of treatment.

By Mr Peter Rhys-Evans
Otolaryngology / ENT

With over 35 years of consultant-grade experience, Mr Peter Rhys-Evans is a leading ENT surgeon in London and one of the UK's foremost head and neck cancer surgeons. His special areas of interest are voice, throat and swallowing problems, sinus and nasal conditions, thyroid and salivary gland diseasebenign growths, and malignant tumours. Mr Rhys-Evans is currently involved in developing new robotic surgical techniques for tumours of the throat. He has been listed in the UK Good Doctor Guide since 1994.

Mr Rhys-Evans oirginally qualified from the University of London in 1971 and underwent specialist training in London and Birmingham. He completed a Postgraduate Degree in Head and Neck Cancer Surgery at the University of Paris, and was later awarded the Lionel College Fellowship to study head and neck reconstructive techniques in America. As Consultant ENT Surgeon at the Queen Elizabeth Hospital in Birmingham, Mr Rhys-Evans was a pioneer in laser conservation surgery and voice construction. He was appointed Chief of ENT/Head and Neck Surgery at The Royal Marsden Hospital in 1986, where he practised until 2017. 

Throughout his career, Mr Rhys-Evans has made a significant contribution to the ENT field, with over 250 publications to his name, hundreds of presentations at major international conferences, and a landmark textbook in 2003 recognised by the University of London as the best international publication in Otolaryngology during the preceding five years. He is the founder and Executive Chairman of The Oracle Trust, which has raised over £6m since 2001 to fund research into new treatments for head and neck cancer.

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