Systemic sclerosis

Systemic sclerosis or scleroderma is a mixed connective tissue disease affecting skin, internal organs, joints and blood vessels. The main symptom of systemic sclerosis is swelling and hardening of the skin, and inflammation and scarring in many parts of the body that cause problems in organs like the heart, lungs, or kidneys, among others. The disease can occur in severe form resulting in death, or mild form in which it manifests itself only in a localized way. Thus, there are two main types of MS. The first is localized scleroderma, which affects only the skin, causing discolored areas, thick grooves or slots, and the second is systemic scleroderma which affects the skin, blood vessels and internal organs. In localized scleroderma there is a variety called linear morphea that occurs most often in children and can cause functional impairment, joint contractures, deformity and neurological manifestations. Treatment of the disease depends on the type and severity of symptoms.

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